The Delta and Omicron variants of SARS-CoV-2: what we know so far

VP Chavda, R Bezbaruah, K Deka, L Nongrang… - Vaccines, 2022 - mdpi.com
The world has not yet completely overcome the fear of the havoc brought by SARS-CoV-2.
The virus has undergone several mutations since its initial appearance in China in …

Mechanistic insights into the immune pathophysiology of COVID-19; an in-depth review

A Shafqat, S Shafqat, SA Salameh, J Kashir… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …

Molnupiravir maintains antiviral activity against SARS-CoV-2 variants and exhibits a high barrier to the development of resistance

JM Strizki, JM Gaspar, JA Howe… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Molnupiravir, an oral prodrug of N-hydroxycytidine (NHC), previously demonstrated broad in
vitro antiviral activity against multiple RNA viruses and has shown a high barrier to the …

Inhalation of ACE2-expressing lung exosomes provides prophylactic protection against SARS-CoV-2

Z Wang, S Hu, KD Popowski, S Liu, D Zhu… - Nature …, 2024 - nature.com
Continued emergence of SARS-CoV-2 variants of concern that are capable of escaping
vaccine-induced immunity highlights the urgency of developing new COVID-19 therapeutics …

Prevalence of medical contraindications to nirmatrelvir/ritonavir in a cohort of hospitalized and nonhospitalized patients with COVID-19

S Lim, CJ Tignanelli, N Hoertel… - Open Forum …, 2022 - academic.oup.com
This analysis describes the prevalence of contraindications to nirmatrelvir/ritonavir among
66 007 patients with coronavirus disease 2019 in a large health care system. A possible …

Recent advances in passive immunotherapies for COVID-19: The Evidence-Based approaches and clinical trials

P Farhangnia, S Dehrouyeh, AR Safdarian… - International …, 2022 - Elsevier
In late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged,
causing a global pandemic called COVID-19. Currently, there is no definitive treatment for …

Demographic and clinical factors associated with reactivity of anti-SARS-CoV-2 antibodies in serbian convalescent plasma donors

J Grujić, N Bujandrić, Z Budakov-Obradović… - International Journal of …, 2021 - mdpi.com
Passive immunotherapy with convalescent COVID-19 plasma (CCP) is used as a
therapeutic procedure in many countries, including Serbia. In this study, we analyzed the …

Circulating Dynamics of SARS‐CoV‐2 Variants between April 2021 and February 2022 in Turkey

M Sayan, A Arikan, M Isbilen - Canadian Journal of Infectious …, 2022 - Wiley Online Library
The diagnosis of new variants and monitoring their potential effects on diagnosis,
therapeutics, and vaccines by genomic sequencing is essential to manage global public …

Understanding COVID-19 vaccines today: Are T-cells key players?

A Shafqat, TZ Arabi, BN Sabbah, HS Abdulkader… - Vaccines, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has heavily mutated since
the beginning of the coronavirus-2019 (COVID-19) pandemic. In this regard, the so-called …

Molecular and clinical epidemiology of SARS-CoV-2 infection among vaccinated and unvaccinated individuals in a large healthcare organization from New Jersey

JR Mediavilla, T Lozy, A Lee, J Kim, VW Kan, E Titova… - Viruses, 2023 - mdpi.com
New Jersey was among the first states impacted by the COVID-19 pandemic, with one of the
highest overall death rates in the nation. Nevertheless, relatively few reports have been …