Background Chronic pain is defined as pain lasting beyond normal tissue healing time,
generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep …

Exercise is an integral part of the rehabilitation of patients suffering a variety of chronic
musculoskeletal conditions, such as fibromyalgia, chronic low back pain and myofascial …

Chronic pain is one of the most prevalent health problems in our modern world, with millions
of people debilitated by conditions such as back pain, headache and arthritis. To address …

Pain reduction is a primary goal of physical therapy for patients who present with acute or
persistent pain conditions. The purpose of this review is to describe a mechanism-based …

The purpose of this article was to examine the effects of acute exercise on pain perception in
healthy adults and adults with chronic pain using meta-analytic techniques. Specifically …

Neuropathic pain, caused by a lesion or disease affecting the somatosensory system, affects
between 3 and 17% of the general population. The treatment of neuropathic pain is …

Objective Increasing evidence purports exercise as a first-line therapeutic for the treatment
of nearly all forms of chronic pain. However, knowledge of efficacious dosing respective to …

Background Primary dysmenorrhea is cramping abdominal pain associated with menses. It
is prevalent, affects quality of life, and can cause absenteeism. Although evidence-based …

Cortical functioning within the default mode network (DMN) and salience network (SN) is
altered in chronic pain patients. The mechanisms underlying these alterations are unknown …

The main focus for the development of adenosine targets as analgesics to date has been A
1 Rs due to its antinociceptive profile in various preclinical pain models. The usefulness of …