Vascular diseases such as atherosclerosis, stroke or myocardial infarction are a significant
public health problem worldwide. Attempts to prevent vascular diseases often imply …

The hemostatic balance, introduced more than 40 years ago, addresses the components
and reactions involved in fibrin turnover. Fibrin is placed in the core of this delicate balance …

The use of oral contraceptives (OC) causes disturbances of the procoagulant, anticoagulant
and fibrinolytic pathways of blood coagulation which may contribute to the increased risk of …

A plausible mechanism to explain thrombotic risk differences associated with the use of
second-and third-generation oral contraceptives (OCs), particularly in carriers of factor …

Venous thrombosis is a multifactorial disease. Multiple interactions between genetic and
environmental factors contribute to the development of the disease. Presently, we know of …

Thrombosis and disseminated intravascular coagulation are common complications of
cancer. Specific conditions associated with cancer such as stasis due to immobilization or …

Endothelial cell protein C receptor (EPCR) enhances the generation of activated protein C
(APC) by the thrombin-thrombomodulin complex. A soluble form of EPCR (sEPCR), which is …

Several hereditary and acquired risk factors for venous thromboembolism (VTE) are
associated with impaired down-regulation of thrombin formation via the protein C pathway …

BACKGROUND: Patients with polycystic ovary syndrome (PCOS) have an increased
prevalence of thrombophilia, leading to higher rates of pregnancy loss. The aim of this study …

OBJECTIVES: Extrahepatic portal venous system thrombosis (EPVST) occurs in 13% of
patients with either recurrent acute (AP) or chronic (CP) alcoholic pancreatitis. The role of …