Metal ions play important roles in natural biological processes, including the activity of RNA
and DNA. Metal ions interact directly with RNA and DNA and they are components of the …

The in vitro and in vivo effects of platinum complexes have been well reported. However, it is
their interactions with biologically relevant structures and biomacromolecules such as DNA …

U okviru ove disertacije opisana je sinteza i karakterizacija dinuklearnih kompleksa Pd (II)
i/ili Pt (II) sa azot-donorskim mostnim (pirazol, 4, 4'-bipiridin, tpdm= derivat benzen-1, 4 …

Molecules that interact with DNA have been studied extensively with the aim of designing
new types of chemotherapy agents and probes for nucleic acid structures. Studying the …

Synthesis of water soluble metal complexes of β-cyclodextrin based ligands is an emergent
field of research in coordination chemistry. The vast interest in this field has stemmed from …

O cancro corresponde a um conjunto vasto de patologias que têm em comum o crescimento
celular desregulado, o que leva à formação de tumores que invadem tecidos adjacentes ou …

Tumor or tumour (originated from Latin 'Tumor'synonymous to swelling) is used to indicate
an abnormal swelling of body part regardless of its pathogenesis (pathologic mechanism of …

Metals are often considered to be toxic for living systems. However, many metal ions are
vital for the human body, since they play a diversity of important roles in biological …

The goal of this research was to design, prepare and study a new class of supermolecules
coupling ruthenium and platinum, which would display covalent binding to DNA. These …

Cancer may be defined as a disease or a group of diseases in which the cells divide and
multiply without control, have the capacity to metastasise in the body, destroy healthy tissue …