This chapter provides a thematic understanding of platinum (Pt) chemistry with the intent to
portray salient biomedical aspects of therapeutically active Pt complexes. Major focus has …

Since the first x-ray structures of DNA revealed that the structure was sensitive to the
environment from which it was crystallized, a combination of biophysical methods has been …

Die moderne Chemotherapie kann vielfältig genutzt werden. Chemotherapieempfindliche
Tumoren können durch eine Mono-oder Kombinationschemotherapie z. T. kurativ behandelt …

Since its approval in 1979 cisplatin has become an important component in chemotherapy
regimes for the treatment of ovarian, testicular, lung and bladder cancers, as well as …

In the last few decades, the constant development of novel microscopy techniques have
created the basis for a new paradigm in the field of biophysics. Single-molecule techniques …

As stated chapter 3, this project deals with the synthesis, characterization, activity in human
ovarian cancer cell lines including cell uptake and level of binding with nuclear DNA, and …

Abstract [Formulae and special characters can only be approximated here. Please see the
pdf version of the Abstract for an accurate reproduction.] Several inert platinum complexes …

Aim. A novel series of TCM-based platinum compounds [Pt (C 8 H 8 O 5)(NH 2 R) 2] 1–5
have been synthesized that purposely integrates into the structure, a modified active …

Our current knowledge on cementitious and binder materials for building and construction is
based on a long history and the use of many different natural materials in their production …

Development of Non-Traditional Platinum Anticancer Agents: trans-Platinum Planar Amine
Compounds and Polynuclear Platinum Compou Page 1 Virginia Commonwealth University …