Chemistry of MRI contrast agents: current challenges and new frontiers

J Wahsner, EM Gale, A Rodríguez-Rodríguez… - Chemical …, 2018 - ACS Publications
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Guidelines for evaluating myocardial cell death

PK Mishra, A Adameova, JA Hill… - American Journal …, 2019 - journals.physiology.org
Cell death is a fundamental process in cardiac pathologies. Recent studies have revealed
multiple forms of cell death, and several of them have been demonstrated to underlie …

Superparamagnetic iron oxide nanoparticles (SPIONs): development, surface modification and applications in chemotherapy

M Mahmoudi, S Sant, B Wang, S Laurent… - Advanced drug delivery …, 2011 - Elsevier
At present, nanoparticles are used for various biomedical applications where they facilitate
laboratory diagnostics and therapeutics. More specifically for drug delivery purposes, the …

Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications

S Laurent, D Forge, M Port, A Roch, C Robic… - Chemical …, 2008 - ACS Publications
In the past decade, the synthesis of superparamagnetic nanoparticles has been intensively
developed not only for its fundamental scientific interest but also for many technological …

Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy

C Tassa, SY Shaw, R Weissleder - Accounts of chemical research, 2011 - ACS Publications
Advances in our understanding of the genetic basis of disease susceptibility coupled with
prominent successes for molecular targeted therapies have resulted in an emerging strategy …

Multimodality imaging probes: design and challenges

A Louie - Chemical reviews, 2010 - ACS Publications
The conundrum of modality selection in clinical diagnostic imaging is that modalities with the
highest sensitivity have relatively poor resolution, while those with high resolution have …

Recent advances in iron oxide nanocrystal technology for medical imaging

C Corot, P Robert, JM Idée, M Port - Advanced drug delivery reviews, 2006 - Elsevier
Superparamagnetic iron oxide particles (SPIO and USPIO) have a variety of applications in
molecular and cellular imaging. Most of the recent research has concerned cellular imaging …

Influence of molecular parameters and increasing magnetic field strength on relaxivity of gadolinium‐ and manganese‐based T1 contrast agents

P Caravan, CT Farrar, L Frullano… - Contrast media & …, 2009 - Wiley Online Library
Simulations were performed to understand the relative contributions of molecular
parameters to longitudinal (r1) and transverse (r2) relaxivity as a function of applied field …

Comprehensive invasive and noninvasive approach to the right ventricle–pulmonary circulation unit: state of the art and clinical and research implications

HC Champion, ED Michelakis, PM Hassoun - Circulation, 2009 - Am Heart Assoc
markers such as right atrial pressure, cardiac output, and mean PAP. 8 Importantly, this
procedure has been shown to be safe, with no deaths reported in the National Institutes of …

Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging

S Bhaskar, F Tian, T Stoeger, W Kreyling… - Particle and fibre …, 2010 - Springer
Nanotechnology has brought a variety of new possibilities into biological discovery and
clinical practice. In particular, nano-scaled carriers have revolutionalized drug delivery …