Chemistry of MRI contrast agents: current challenges and new frontiers
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …
performed annually around the world. The contrast agents, which improve diagnostic …
Guidelines for evaluating myocardial cell death
Cell death is a fundamental process in cardiac pathologies. Recent studies have revealed
multiple forms of cell death, and several of them have been demonstrated to underlie …
multiple forms of cell death, and several of them have been demonstrated to underlie …
Superparamagnetic iron oxide nanoparticles (SPIONs): development, surface modification and applications in chemotherapy
At present, nanoparticles are used for various biomedical applications where they facilitate
laboratory diagnostics and therapeutics. More specifically for drug delivery purposes, the …
laboratory diagnostics and therapeutics. More specifically for drug delivery purposes, the …
Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications
S Laurent, D Forge, M Port, A Roch, C Robic… - Chemical …, 2008 - ACS Publications
In the past decade, the synthesis of superparamagnetic nanoparticles has been intensively
developed not only for its fundamental scientific interest but also for many technological …
developed not only for its fundamental scientific interest but also for many technological …
Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy
C Tassa, SY Shaw, R Weissleder - Accounts of chemical research, 2011 - ACS Publications
Advances in our understanding of the genetic basis of disease susceptibility coupled with
prominent successes for molecular targeted therapies have resulted in an emerging strategy …
prominent successes for molecular targeted therapies have resulted in an emerging strategy …
Multimodality imaging probes: design and challenges
A Louie - Chemical reviews, 2010 - ACS Publications
The conundrum of modality selection in clinical diagnostic imaging is that modalities with the
highest sensitivity have relatively poor resolution, while those with high resolution have …
highest sensitivity have relatively poor resolution, while those with high resolution have …
Recent advances in iron oxide nanocrystal technology for medical imaging
C Corot, P Robert, JM Idée, M Port - Advanced drug delivery reviews, 2006 - Elsevier
Superparamagnetic iron oxide particles (SPIO and USPIO) have a variety of applications in
molecular and cellular imaging. Most of the recent research has concerned cellular imaging …
molecular and cellular imaging. Most of the recent research has concerned cellular imaging …
Influence of molecular parameters and increasing magnetic field strength on relaxivity of gadolinium‐ and manganese‐based T1 contrast agents
Simulations were performed to understand the relative contributions of molecular
parameters to longitudinal (r1) and transverse (r2) relaxivity as a function of applied field …
parameters to longitudinal (r1) and transverse (r2) relaxivity as a function of applied field …
Comprehensive invasive and noninvasive approach to the right ventricle–pulmonary circulation unit: state of the art and clinical and research implications
HC Champion, ED Michelakis, PM Hassoun - Circulation, 2009 - Am Heart Assoc
markers such as right atrial pressure, cardiac output, and mean PAP. 8 Importantly, this
procedure has been shown to be safe, with no deaths reported in the National Institutes of …
procedure has been shown to be safe, with no deaths reported in the National Institutes of …
Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging
Nanotechnology has brought a variety of new possibilities into biological discovery and
clinical practice. In particular, nano-scaled carriers have revolutionalized drug delivery …
clinical practice. In particular, nano-scaled carriers have revolutionalized drug delivery …