Central nervous system (CNS) involvement is a serious but often underdiagnosed
complication of hematological malignancies. Currently, the gold standard to detect CNS …

Background Accurate disease detection is integral to risk stratification in B‐cell acute
lymphoblastic leukemia (ALL). The gold standard used to evaluate response in the United …

Background The cobas® epidermal growth factor receptor (EGFR) Mutation Test v2
designed for cell‐free DNA (cf DNA) is approved as a companion diagnostic for osimertinib …

Objectives: To determine whether RPMI medium can be used to preserve cell morphology in
pleural/peritoneal effusion samples. Method and Material: The study was conducted on 30 …

Background Because of fast leucocyte degeneration in cerebrospinal fluid (CSF) laboratory
examinations of CSF samples should be performed approximately within 30 min after …

T he lumbar puncture (spinal tap) was introduced in 1891, 1, 2 and in 1904 a French
neurologist first described malignant cells in cerebrospinal fluid (CSF). 3 Since then …

Introduction: The cytological examination of cerebrospinal fluid (CSF) is an important
investigation in the workup of various inflammatory, malignant, or traumatic disorders of the …

Objectives To examine the diagnostic utility of canine cerebrospinal fluid samples collected
into tubes containing ethylenediaminetetraacetic acid (EDTA) with and without the addition …

Background Reporting cerebrospinal fluid (CSF) cytology within a narrow time frame is
crucial as it is often indicated in critically ill patients and moreover, the cells in CSF are …

Introduction: In effusion cytology, immunocytochemistry is a useful staining approach to
provide important information for diagnosis. Effusion cytology is performed not only for …