Migraine is a common and highly disabling neurological disorder associated with a high
socioeconomic burden. Effective migraine management depends on adequate patient …

Headache is the most frequent neurological symptom and the most prevalent pain in
children and adolescents, and constitutes a serious health problem that may lead to …

International Headache Society Clinical Trials Subcommittee members: Peer Tfelt-Hansen
(chairman)(Denmark) 1, Julio Pascual (vice-chairman)(Spain) 2, Nabih Ramadan (vice …

OBJECTIVE: Our goal was to investigate the pooled evidence for the effectiveness of using
biofeedback to reduce childhood migraine. DATA SOURCES: A systematic search was …

Chronic pain is an important clinical problem affecting significant numbers of children and
their families. The severity and impact of chronic pain on everyday function is shaped by the …

Primary headache disorders are frequently encountered in the pediatric population. The
therapeutic approach consists of a multimodal program, including lifestyle modification …

The recognition of the diagnosis of migraine in children is increasing. Early and aggressive
treatment of migraine in this population with the use of over-the-counter medications has …

Background: Plasma calcitonin gene-related peptide (CGRP) plays a key role in the
migraine pathophysiology. This study aimed to investigate its role in predicting diagnosis …

Migraine is one of the most common neurological disorder, which has long been related to
brain serotonin (5-HT) depletion and neuro-inflammation. Despite many treatment options …

Purpose To determine the pervasiveness of opioid prescribing for adolescents with
headache and patient and provider characteristics associated with likelihood of opioid …