Twenty to forty one percent of the world's population is either transiently or permanently
colonized by the Gram-positive bacterium, Staphylococcus aureus. In 2017, the CDC …

Abstract The Many Hosts of Mycobacteria (MHM) meeting series brings together basic
scientists, clinicians and veterinarians to promote robust discussion and dissemination of …

Background Microbial biofilms, as a hallmark of cystic fibrosis (CF) lung disease and other
chronic infections, remain a desirable target for antimicrobial therapy. These biopolymer …

We are entering the post-antibiotic era. Antimicrobial resistance (AMR) is a critical problem
in chronic lung infections resulting in progressive respiratory failure and increased mortality …

The phenomenon of antimicrobial resistance (AMR) is a critical global health challenge, with
prospects indicating its potential to become the leading cause of death worldwide in the …

Armed with an arsenal of protein secretion systems, antibiotic efflux pumps, and the
occasional proclivity for explosive self-destruction, Pseudomonas aeruginosa has become a …

Objectives Structural or mucus hypersecretory pulmonary diseases such as cystic fibrosis
(CF), wherein viscous mucus accumulates and clearance functions are impaired …

Polymyxin B and ethylenediaminetetraacetic acid are antimicrobials possessing antibiofilm
activity. They act by displacement and chelation, respectively, of divalent cations in bacterial …

Bacterial pneumonia greatly contributes to the disease burden and mortality of lower
respiratory tract infections among all age groups and risk profiles. Therefore, laboratory …

The airways of cystic fibrosis (CF) patients are colonized by many pathogens and the most
common is Pseudomonas aeruginosa, an environmental pathogen that is able to infect …