BACKGROUND Tertiary lymphoid structures (TLSs) are organized aggregates of immune
cells that form postnatally in nonlymphoid tissues. TLSs are not found under physiological …

The generation of anti-tumor immunity in the draining lymph nodes is known as the cancer
immunity cycle. Accumulating evidence supports the occurrence of such a cycle at tumor …

Ectopic lymphoid-like structures often develop at sites of inflammation where they influence
the course of infection, autoimmune disease, cancer and transplant rejection. These …

The characterization of the microenvironment of human tumors led to the description of
tertiary lymphoid structures (TLS) characterized by mature dendritic cells in a T‐cell zone …

Over the past few decades, inflammation has been recognized as a major risk factor for
various human diseases. Acute inflammation is short-term, self-limiting and it's easy for host …

Thousands of literatures have described the diverse role of ginseng in physiological
processes such as cancer, neurodegenerative disorders, insulin resistance, and …

Chronically inflamed tissues commonly accrue lymphocyte aggregates that facilitate local T
cell-B cell interactions. These aggregates can range from small, loosely arranged …

Ectopic lymphoid neogenesis often occurs in the target tissues of patients with chronic
rheumatic autoimmune diseases such as rheumatoid arthritis, Sjögren syndrome and other …

Tertiary lymphoid structures (TLS) are frequently observed in target organs of autoimmune
diseases. TLS present features of secondary lymphoid organs such as segregated T and B …

De novo formation of tertiary lymphoid structures (TLS) has been described in lung cancers.
Intratumoral TLS seem to be functional and are associated with a long-term survival for lung …