In eukaryotic cells, the enclosure of the genetic information in the nucleus allows the spatial
and temporal separation of DNA replication and transcription from cytoplasmic protein …

The mental retardation protein FMRP is involved in the transport of mRNAs and their
translation at synapses. Patients with fragile X syndrome, in whom FMRP is absent or …

To understand the gene network controlling tolerance to cold stress, we performed an
Arabidopsis thaliana genome transcript expression profile using Affymetrix GeneChips that …

The structure, function and reactions of nucleic acids are central to molecular biology and
are crucial for the understanding of complex biological processes involved. Revised and …

Localization of β-actin messenger RNA to sites of active actin polymerization modulates cell
migration during embryogenesis, differentiation and possibly carcinogenesis,,,,. This …

Proper neuronal function and several forms of synaptic plasticity are highly dependent on
precise control of mRNA translation, particularly in dendrites. We find that eIF4AIII, a core …

The expression of genes, both coding and noncoding, can be significantly influenced by
RNA structural features of their corresponding transcripts. There is by now mounting …

Localization of maternal mRNAs in many developing organisms provides the basis for both
initial polarity during oogenesis and patterning during embryogenesis. Prominent examples …

The dendritic transport and local translation of mRNA may be an essential mechanism to
regulate synaptic growth and plasticity. We investigated the molecular mechanism and …

In eukaryotes, the entwined pathways of RNA transport and local translational regulation are
key determinants in the spatio-temporal articulation of gene expression. One of the main …