Integration of peripheral blood‐and tissue‐based biomarkers of response to immune checkpoint blockade in urothelial carcinoma
RS Vanguri, JW Smithy, Y Li, M Zhuang… - The Journal of …, 2023 - Wiley Online Library
As predictive biomarkers of response to immune checkpoint inhibitors (ICIs) remain a major
unmet clinical need in patients with urothelial carcinoma (UC), we sought to identify tissue …
unmet clinical need in patients with urothelial carcinoma (UC), we sought to identify tissue …
Correlations between Circulating and Tumor-Infiltrating CD4+ Treg Subsets with Immune Checkpoints in Colorectal Cancer Patients with Early and Advanced Stages
The existence of various T regulatory cell (Treg) subsets in colorectal cancer (CRC) could
play a variety of functions in the regulation of anti-cancer immunity. We studied correlations …
play a variety of functions in the regulation of anti-cancer immunity. We studied correlations …
[HTML][HTML] ALDH2 as an immunological and prognostic biomarker: Insights from pan-cancer analysis
X Shen, Z Yan, Y Huang, Q Zhu, G Zhang, H Ci, Q Wu… - Medicine, 2024 - journals.lww.com
Abstract Aldehyde dehydrogenase 2 (ALDH2) plays a critical role in safeguarding cells
against acetaldehyde toxicity and is closely linked to human metabolism. Nevertheless, the …
against acetaldehyde toxicity and is closely linked to human metabolism. Nevertheless, the …
[HTML][HTML] Co-expression of PD-1 with TIGIT or PD-1 with TIM-3 on tumor-infiltrating CD8+ T cells showed synergistic effects on improved disease-free survival in …
A Meyiah, GM Chalbatani, MA Al-Mterin… - International …, 2023 - Elsevier
Immune checkpoints (ICs) are highly expressed on tumor-infiltrating immune cells (TIICs) in
different malignancies, including colorectal cancer (CRC). T cells play crucial roles in …
different malignancies, including colorectal cancer (CRC). T cells play crucial roles in …