In recent years, the biological role of changes in physical factors in carcinogenesis and
progression has attracted increasing attention. Matrix stiffness, also known as ECM stress, is …

Elastography has emerged as a preferred non-invasive imaging technique for the clinical
assessment of liver fibrosis. Elastography methods provide liver stiffness measurement …

Background MR elastography (MRE) has been shown to have excellent performance for
noninvasive liver fibrosis staging. However, there is limited knowledge regarding the …

Nonalcoholic fatty liver disease (NAFLD), a spectrum of liver diseases characterized by
excessive fat accumulation, is the leading cause of chronic liver disease. The global …

X-linked myotubular myopathy (XLMTM) is a rare, life-threatening congenital myopathy
characterized by profound skeletal muscle weakness, respiratory distress, and motor …

OBJECTIVES: To determine the prevalence of alternative causes of liver disease in a cohort
of youth with overweight and obesity undergoing evaluation for suspected nonalcoholic fatty …

Background Quantitative US techniques can be used to identify changes of liver disease, but
data regarding their diagnostic performance and relationship to MRI measures are sparse …

Background Pediatric radiologists can identify a liver ultrasound (US) pattern predictive of
progression to advanced liver disease. However, reliably discriminating these US patterns …

Background: Elastography can be measured with different imaging techniques and is
increasingly used for noninvasive assessment of hepatic fibrosis. Little is known about the …

Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in
children. While environmental factors are major contributors to early onset, children have …