Invasive fungal diseases are rare in individuals with intact immunity. This, together with the
fact that there are only a few species that account for most mycotic diseases, implies a …

Neutrophils are crucial elements of innate immune system, which assure host defense via a
range of effector functions, such as phagocytosis, degranulation, and NET formation. The …

Neutrophil extracellular traps (NETs) are DNA scaffolds coated with granule proteins that are
released by neutrophils to ensnare and kill bacteria. NET formation occurs in response to …

Neutrophil extracellular traps (NETs) are web-like extrusions of genetic material, which are
released upon neutrophil activation. NETs consist of a chromatin substructure, onto which a …

Candida auris is among the most important emerging fungal pathogens, yet mechanistic
insights into its immune recognition and control are lacking. Here, we integrate …

Whilst the majority of individuals infected with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), the causative pathogen of COVID-19, experience mild to …

Invasive candidiasis encompassing Candida bloodstream infections and deep-seated
candidiasis can become a persistent health problem. These infections are caused by …

Neutrophil extracellular traps (NETs) have been identified as one pathogenetic trigger in
severe COVID-19 cases and therefore well-described animal models to understand the …

β2 integrins are heterodimeric surface receptors composed of a variable α (CD11a-CD11d)
and a constant β (CD18) subunit and are specifically expressed by leukocytes. The α …

Lanthipeptides are ribosomally synthesized and posttranslationally modified peptides, with
modifications that are incorporated during biosynthesis by dedicated enzymes. Various …