The role of immune inflammation in aneurysmal subarachnoid hemorrhage

Z Zhang, Y Fang, C Lenahan, S Chen - Experimental Neurology, 2021 - Elsevier
Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating disease, which mainly
caused by the rupture of an intracranial aneurysm. Clinical trials have demonstrated that …

Disturbed flow's impact on cellular changes indicative of vascular aneurysm initiation, expansion, and rupture: A pathological and methodological review

K Sunderland, J Jiang, F Zhao - Journal of cellular physiology, 2022 - Wiley Online Library
Aneurysms are malformations within the arterial vasculature brought on by the structural
breakdown of the microarchitecture of the vessel wall, with aneurysms posing serious health …

[HTML][HTML] Shedding the light on the natural history of intracranial aneurysms: an updated overview

A Giotta Lucifero, M Baldoncini, N Bruno, R Galzio… - Medicina, 2021 - mdpi.com
The exact molecular pathways underlying the multifactorial natural history of intracranial
aneurysms (IAs) are still largely unknown, to the point that their understanding represents an …

Regular medication as a risk factor for intracranial aneurysms: A comparative case–control study

R Jabbarli, M Darkwah Oppong, M Chihi… - European stroke …, 2023 - journals.sagepub.com
Background: Previous medical history strongly contributes to the genesis of intracranial
aneurysms (IA). A possible impact of regular medication on the occurrence of abdominal …

Suppression of COX-2/PGE2 levels by carbazole-linked triazoles via modulating methylglyoxal-AGEs and glucose-AGEs–induced ROS/NF-κB signaling in monocytes

H Jahan, NN Siddiqui, S Iqbal, FZ Basha, S Shaikh… - Cellular …, 2022 - Elsevier
Chronic hyperglycemia favours the formation of advanced glycation end products (AGEs)
which are responsible of many diabetic vascular complications. Keeping in view the …

[HTML][HTML] Endovascular biopsy of vertebrobasilar aneurysm in patient with polyarteritis Nodosa

KH Narsinh, K Narsinh, DB McCoy, Z Sun… - Frontiers in …, 2021 - frontiersin.org
Background and Purpose: The management of unruptured intracranial aneurysms remains
controversial. The decisions to treat are heavily informed by estimated risk of bleeding …

[HTML][HTML] Progressive volume reduction and long-term aneurysmal collapse following flow diversion treatment of giant and symptomatic cerebral aneurysms

K Sirakova, M Penkov, S Matanov, K Minkin… - Frontiers in …, 2022 - frontiersin.org
Background The primary goal of conventional endovascular and microvascular approaches
is the clinical and radiological resolution of the symptomatic aneurysm-induced mass effect …

[HTML][HTML] Effect of combined acetylsalicylic acid and statins treatment on intracranial aneurysm rupture

M Terceño, S Remollo, Y Silva, S Bashir, M Werner… - PLoS …, 2021 - journals.plos.org
Background Acetylsalicylic acid (ASA) and statins have been identified as potentially
reducing the risk of intracranial aneurysms (IA) rupture. We aim to determine the effect of this …

[HTML][HTML] On the potential self-amplification of aneurysms due to tissue degradation and blood flow revealed from FSI simulations

H Wang, D Balzani, V Vedula, K Uhlmann… - Frontiers in …, 2021 - frontiersin.org
Tissue degradation plays a crucial role in the formation and rupture of aneurysms. Using
numerical computer simulations, we study the combined effects of blood flow and tissue …

In the wall lies the truth: a systematic review of diagnostic markers in intracranial aneurysms

R Jabbarli, L Rauschenbach, TF Dinger… - Brain …, 2020 - Wiley Online Library
Objective: Despite recent advances in molecular biology and genetics, the development of
intracranial aneurysms (IA) is still poorly understood. Elucidation of the processes occurring …