Inhibitory immune checkpoint (ICP) molecules are pivotal in inhibiting innate and acquired
antitumor immune responses, a mechanism frequently exploited by cancer cells to evade …

Cancer cells largely rely on aerobic glycolysis or the Warburg effect to generate essential
biomolecules and energy for their rapid growth. The key modulators in glycolysis including …

Simple Summary The breakdown of glucose in the glycolytic pathway provides energy and
essential building blocks to support cell division and growth in important body processes …

由TP53 编码的P53 蛋白是防止细胞癌变所需的关键因子, 有广泛而强大的功能. P53
在诱导细胞周期停滞, DNA 损伤修复, 细胞凋亡和衰老等过程中发挥重要作用 …

Although elevated glycolysis has been widely recognized as a hallmark for highly
proliferating cells like stem cells and cancer, its regulatory mechanisms are still being …

Background This study aimed to investigate the effects of the volume and time of hydration
on the quantification of healthy tissue uptake for 2-deoxy-2-[18 F]-fluoro-D-glucose (18 F …

Background Glycolysis plays significant roles in tumor progression and immune response.
However, the exact role of glycolysis in prognosis and immune regulation has not been …

P53 is a key factor encoded by the TP53, and it prevents cells from becoming cancerous and
has a wide range of powerful functions. p53 is found to play an important role in inducing …