[HTML][HTML] Genetics of the human Y chromosome and its association with male infertility

S Colaco, D Modi - Reproductive biology and endocrinology, 2018 - Springer
The human Y chromosome harbors genes that are responsible for testis development and
also for initiation and maintenance of spermatogenesis in adulthood. The long arm of the Y …

[HTML][HTML] Oxidative stress impairs function and increases redox protein modifications in human spermatozoa

T Morielli, C O'Flaherty - Reproduction, 2015 - rep.bioscientifica.com
Oxidative stress, generated by excessive reactive oxygen species (ROS) or decreased
antioxidant defenses (and possibly both), is associated with male infertility. Oxidative stress …

[HTML][HTML] Mystery of idiopathic male infertility: is oxidative stress an actual risk?

G Aktan, S Doğru-Abbasoğlu, C Küçükgergin… - Fertility and sterility, 2013 - Elsevier
OBJECTIVE: To study the role of oxidative stress in sperm dysfunction in Turkish idiopathic
infertile men. DESIGN: Prospective study. SETTING: Medical laboratory. PATIENT (S) …

Prospects for FSH treatment of male infertility

M Simoni, G Brigante, V Rochira… - The Journal of …, 2020 - academic.oup.com
Context Despite the new opportunities provided by assisted reproductive technology (ART),
male infertility treatment is far from being optimized. One possibility, based on …

[HTML][HTML] The fate of leydig cells in men with spermatogenic failure

D Adamczewska, J Słowikowska-Hilczer… - Life, 2022 - mdpi.com
The steroidogenic cells in the testicle, Leydig cells, located in the interstitial compartment,
play a vital role in male reproductive tract development, maintenance of proper …

[HTML][HTML] Detection of AZF microdeletions and reproductive hormonal profile analysis of infertile sudanese men pursuing assisted reproductive approaches

HOA Elsaid, T Gadkareim, T Abobakr, E Mubarak… - BMC urology, 2021 - Springer
Background Male factor is the major contributor in roughly half of infertility cases. Genetic
factors account for 10–15% of male infertility. Microdeletions of azoospermia factors (AZF) …

[HTML][HTML] Y chromosome microdeletions in infertile men with non-obstructive azoospermia and severe oligozoospermia

SY Kim, HJ Kim, BY Lee, SY Park… - Journal of reproduction …, 2017 - ncbi.nlm.nih.gov
Background: The purpose of the study was to investigate the frequencies and types of Y
chromosome microdeletions in infertile men and to analyze the relationship between the …

Peroxiredoxin 6 regulates the phosphoinositide 3-kinase/AKT pathway to maintain human sperm viability

MC Fernandez, A Yu, AR Moawad… - Molecular Human …, 2019 - academic.oup.com
Peroxiredoxins (PRDXs) are antioxidant enzymes proven to control the levels of reactive
oxygen species (ROS) and to avoid oxidative damage in the spermatozoon. Previously, we …

[HTML][HTML] Assessment of the level of trace element zinc in seminal plasma of males and evaluation of its role in male infertility

MS Khan, S Zaman, M Sajjad, M Shoaib… - International Journal of …, 2011 - journals.lww.com
Background: Male infertility is a serious problem all over the world. Nutritional deficiency of
trace element Zinc (Zn) may play a role in male infertility as Zn plays an important role not …

Clinical diagnostic testing for the cytogenetic and molecular causes of male infertility: the Mayo Clinic experience

SE Hofherr, AE Wiktor, BR Kipp, DB Dawson… - Journal of assisted …, 2011 - Springer
Purpose Approximately 8% of couples attempting to conceive are infertile and male infertility
accounts for approximately 50% of infertility among couples. Up to 25% of males with non …