Second harmonic generation microscopy: a powerful tool for bio-imaging

A Aghigh, S Bancelin, M Rivard, M Pinsard… - Biophysical …, 2023 - Springer
Second harmonic generation (SHG) microscopy is an important optical imaging technique in
a variety of applications. This article describes the history and physical principles of SHG …

More than double the fun with two-photon excitation microscopy

P Luu, SE Fraser, F Schneider - Communications Biology, 2024 - nature.com
For generations researchers have been observing the dynamic processes of life through the
lens of a microscope. This has offered tremendous insights into biological phenomena that …

Fast intraoperative histology-based diagnosis of gliomas with third harmonic generation microscopy and deep learning

M Blokker, PCW Hamer, P Wesseling, ML Groot… - Scientific reports, 2022 - nature.com
Management of gliomas requires an invasive treatment strategy, including extensive
surgical resection. The objective of the neurosurgeon is to maximize tumor removal while …

Effect of out of plane orientation on polarization second harmonic generation of single collagen fibrils

MA Harvey, R Cisek, D Tokarz… - Biomedical Optics Express, 2023 - opg.optica.org
Second harmonic generation (SHG) microscopy has emerged as a powerful technique for
visualizing collagen organization within tissues. Amongst the many advantages of SHG is its …

Theoretical Understanding of Nonlinear Optical Properties in Solids: A Perspective

S Han, L Ye, Y Li, B Huang - The Journal of Physical Chemistry …, 2024 - ACS Publications
Nonlinear optical (NLO) crystals have become a hot topic in chemical science and material
physics, due to their essential role in laser technology, optical information, optoelectronics …

Aberration free synthetic aperture second harmonic generation holography

G Murray, J Field, M Xiu, Y Farah, L Wang, O Pinaud… - Optics …, 2023 - opg.optica.org
Second harmonic generation (SHG) microscopy is a valuable tool for optical microscopy.
SHG microscopy is normally performed as a point scanning imaging method, which lacks …

A “turn off” sensor for highly sensitive and selective detection of syringaldehyde typed aromatic aldehydes based on an amino-functionalized metal–organic framework

T Wang, S Zhu, X Nan, L He, P Bai, Z Liu - Microchemical Journal, 2023 - Elsevier
Aromatic aldehydes are important chemical raw materials with serious harm to human
health and environment. Sensitive, selective and rapid detection of these compounds is of …

Label-free multimodal nonlinear optical microscopy reveals features of bone composition in pathophysiological conditions

B Talone, A Bresci, F Manetti, F Vernuccio… - … in Bioengineering and …, 2022 - frontiersin.org
Bone tissue features a complex microarchitecture and biomolecular composition, which
determine biomechanical properties. In addition to state-of-the-art technologies, innovative …

High-Resolution Quantitative Phase Microscopy with Second-Harmonic Generation and Structured Illumination from a -Space Formulation

N Zhou, A Zheng, KKY Wong, R Zhou - Physical Review Applied, 2022 - APS
We propose a high-resolution label-free two-dimensional imaging method by introducing
second-harmonic generation (SHG) and structured illumination in quantitative phase …

Live mapping of the brain extracellular matrix and remodeling in neurological disorders

X Ge, X Xu, Q Cai, H Xiong, C Xie, Y Hong… - Small …, 2024 - Wiley Online Library
Live imaging of the brain extracellular matrix (ECM) provides vital insights into changes that
occur in neurological disorders. Current techniques such as second or third‐harmonic …