Intra-articular drug delivery has a number of advantages over systemic administration;
however, for the past 20 years, intra-articular treatment options for the management of knee …

Osteoarthritis is a condition caused in part by injury, loss of cartilage structure and function,
and an imbalance in inflammatory and anti-inflammatory pathways. It primarily affects the …

OBJECTIVES To investigate whether subjects with knee osteoarthritis (OA) have reduced
static postural control, knee proprioceptive acuity, and maximal voluntary contraction (MVC) …

Objective To examine the mechanism of interleukin‐1 (IL‐1)–induced collagenase 3 (matrix
metalloproteinase 13 [MMP‐13]) gene expression in cultured chondrocytes for the purpose …

Introduction Currently available treatments for osteoarthritis (OA) are restricted to
nonsteroidal anti-inflammatory drugs, which exhibit numerous side effects and are only …

Objective Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that plays a key role in the
pathogenesis of osteoarthritis (OA). Growth factors (GFs) capable of antagonizing the …

Objective To investigate balance control according to the severity of knee osteoarthritis (OA)
using clinical tests and Tetra-ataxiometric posturography (Tetrax®). Method A total 80 …

Objective In osteoarthritis (OA), a combination of biochemical and biomechanical factors
may damage both menisci and articular cartilage. Nitric oxide (NO) and prostaglandin E2 …

Objective The chemokine family of secreted proteins regulates cellular activities through
interaction with G protein‐coupled chemokine receptors. The aim of this study was to …

Osteoarthritis (OA) is common in the elderly, but also affects younger people. The disease
symptoms are debilitating and, as well as causing physical impairment, can affect the …