Osteoarthritis (OA) is common in the elderly, but also affects younger people. The disease
symptoms are debilitating and, as well as causing physical impairment, can affect the …

Osteoarthritis is a condition caused in part by injury, loss of cartilage structure and function,
and an imbalance in inflammatory and anti-inflammatory pathways. It primarily affects the …

Osteoarthritis (OA) is a disease of high ethical and economical importance. In advanced
stages, the patients suffer from severe pain and restriction of mobility. The consequence in …

Abstract Background/Objective Osteoarthritis (OA) is a multifactorial joint disease associated
with the deterioration of chondrocytes and inflammation. Treatment of OA is only aimed at …

Natural products, secondary metabolites, isolated from plants, animals and microbes are
important sources for bioactive molecules that in many cases have been developed into …

Despite the recognition that degenerative cartilage disorders like osteoarthritis (OA) and
osteochondritis dissecans (OCD) may have nutritional abnormalities at the root of their …

Intra-articular drug delivery is the preferred standard for targeting pharmacologic treatment
directly to joints to reduce undesirable side effects associated with systemic drug delivery. In …

OBJECTIVE: Interleukin-6 (IL-6) is expressed in osteoarthritic joints but its function in
osteoarthritis (OA) is unknown. To study this, spontaneous and experimental OA were …

In normal hyaline cartilage the predominant collagen type is collagen type II along with its
associated collagens, for example, types IX and XI, produced by normal chondrocytes. In …

Objective Human chondrocytes produce different C‐X‐C and C‐C chemokines under basal
conditions and upon activation with proinflammatory cytokines. We investigated whether …