Subchondral tibial bone mineral density predicts future joint space narrowing at the medial femoro-tibial compartment in patients with knee osteoarthritis

O Bruyère, C Dardenne, E Lejeune, B Zegels, A Pahaut… - Bone, 2003 - Elsevier
Preliminary studies have shown that dual-energy X-ray absorptiometry (DXA) produces
images of sufficient quality for a precise and accurate measurement at density of the …

RANKL/OPG ratio and DKK-1 expression in primary osteoblastic cultures from osteoarthritic and osteoporotic subjects

A Corrado, A Neve, A Macchiarola, A Gaudio… - The Journal of …, 2013 - jrheum.org
Objective. To evaluate the expression of Dickkopf-1 protein factor (DKK-1), DKK-2, and β-
catenin, components of the Wnt pathway, in human osteoarthritic (OA) and osteoporotic (OP) …

Cartilage oligomeric matrix protein is involved in human limb development and in the pathogenesis of osteoarthritis

S Koelling, TS Clauditz, M Kaste, N Miosge - Arthritis research & therapy, 2006 - Springer
As a member of the thrombospondin gene family, cartilage oligomeric protein (COMP) is
found mainly in the extracellular matrix often associated with cartilage tissue. COMP exhibits …

Biochemical markers of bone and cartilage remodeling in prediction of longterm progression of knee osteoarthritis.

O Bruyere, JH Collette, O Ethgen, LC Rovati… - The Journal of …, 2003 - jrheum.org
OBJECTIVE: To investigate the relationship between biochemical markers of bone and
cartilage remodeling and severity or progression (symptoms and structure) of knee …

Osteoarthritis, magnetic resonance imaging, and biochemical markers: a one year prospective study

O Bruyere, J Collette, M Kothari, S Zaim… - Annals of the …, 2006 - ard.bmj.com
Objective: To investigate the relation between biochemical markers of bone, cartilage, and
synovial remodelling and the structural progression of knee osteoarthritis. Methods: 62 …

[HTML][HTML] Sorbitol-modified hyaluronic acid reduces oxidative stress, apoptosis and mediators of inflammation and catabolism in human osteoarthritic chondrocytes

JM Mongkhon, M Thach, Q Shi, JC Fernandes… - Inflammation …, 2014 - Springer
Objective and design Our study was designed to elucidate the precise molecular
mechanisms by which sorbitol-modified hyaluronic acid (HA/sorbitol) exerts beneficial …

A mechanistic review on growing multiple therapeutic applications of lutein and its global market research

AS Akkewar, KMA Mishra, MG Kamble… - Phytotherapy …, 2024 - Wiley Online Library
Lutein is a naturally occurring carotenoid synthesized by plants and algae that has a
beneficial effect on several biological processes and associated ailments. Its immediate …

Sex differences of chondrogenic progenitor cells in late stages of osteoarthritis

S Koelling, N Miosge - Arthritis & Rheumatism, 2010 - Wiley Online Library
Objective Osteoarthritis (OA), a mainly degenerative disease, is known to be multifactorial in
origin. Gene expression patterns vary between populations and sexes. Sex hormone …

Recent Advances in Synthesis and Medicinal Evaluation of 1, 2‐Benzothiazine Analogues

R Reetu, R Gujjarappa… - Asian Journal of Organic …, 2022 - Wiley Online Library
Benzothiazines are one of the significant nitrogen containing heterocyclic scaffolds which
are found to be multipurpose in the fields of drug discovery and medicinal chemistry. They …

Stimulation of hyaluronan metabolism by interleukin‐1α in human articular cartilage

Y Nishida, AL D'Souza, EJMA Thonar… - … : Official Journal of the …, 2000 - Wiley Online Library
Objective To determine the effects of interleukin‐1α (IL‐1α) on the expression of hyaluronan
synthase (HAS), CD44, and aggrecan in human articular chondrocytes, and to assess the …