Page 1 ADVANCES IN ANATOMY, EMBRYOLOGY AND CELL BIOLOGY Ali Mobasheri
Carolyn A. Bondy Kelle Moley Alexandrina Ferreira Mendes Susanna Carvalho Rosa …

OBJECTIVE: Disturbances of the proteoglycan metabolism play an essential role in the
pathology of osteoarthritis. The extracellular matrix proteoglycan, perlecan, has lately been …

Objective This study was undertaken to test the hypothesis that abnormalities of the
subchondral bone can result in osteoarthritis (OA). Methods We used a knockin model of …

Objective Inflammation is implicated to be involved in the pathogenesis of osteoarthritis
(OA). CXCL12, also known as stromal cell-derived factor, is the unique identified natural …

Background This study was performed to evaluate the antioxidative and anti-inflammatory
effects of vitamin E on oxidative stress in the plasma, synovial fluid, and synovial tissue of …

To examine the role of connective tissue growth factor CCN2/CTGF (CCN2) in the
maintenance of the articular cartilaginous phenotype, we analyzed knee joints from aging …

Mesenchymal stem cells (MSCs) play a crucial role in maintaining bone homeostasis and
are extensively explored for cell therapy in various bone‐related diseases. In addition to …

Objective To investigate the incidence and severity of osteoarthritis (OA) and the effects of
voluntary wheel running in normal mice and mice carrying either a targeted inactivation of …

Background Osteoarthritis, a common degenerative disease of articular cartilage, is
characterized by degeneration of articular cartilage, changes in subchondral bone structure …

In response to evolutionary selective pressure, prokaryotes have developed a rich array of
secondary metabolites, some of which may be inhibitory to the innate immune system and …