[HTML][HTML] Cartilage oligomeric matrix protein-inflammation biomarker in knee osteoarthritis

S Živanović, LP Rackov, A Živanović… - Bosnian Journal of …, 2011 - ncbi.nlm.nih.gov
Chondrocytes and synovial cells synthesize Cartilage Oligomeric Matrix Protein (COMP)
when activated by proinflammatory cytokines. The aim of this study was to analyze and …

Alternative therapy of earth elements increases the chondroprotective effects of chondroitin sulfate in mice

M Caraglia, S Beninati, G Giuberti… - … & molecular medicine, 2005 - nature.com
The administration of mineral sulphur water is an alternative experimental approach for the
treatment of rheumatic diseases, such as osteoarthritis (OA), that cause the degeneration of …

Primary knee osteoarthritis increases the risk of falling

G Tasci Bozbas, OF Sendur… - Journal of Back and …, 2017 - content.iospress.com
OBJECTIVES: The aim of this study was to investigate the effect of primary knee
osteoarthritis on the risk of falling. MATERIALS AND METHODS: One hundred participants …

[HTML][HTML] The interplay between biochemical mediators and mechanotransduction in chondrocytes: Unravelling the differential responses in primary knee osteoarthritis

M Segarra-Queralt, K Crump, A Pascuet-Fontanet… - Physics of life …, 2024 - Elsevier
In primary or idiopathic osteoarthritis (OA), it is unclear which factors trigger the shift of
articular chondrocyte activity from pro-anabolic to pro-catabolic. In fact, there is a controversy …

New aspects of the pathogenesis of osteoarthritis: the role of fibroblast-like chondrocytes in late stages of the disease

F Tesche, N Miosge - Histology and histopathology, 2005 - digitum.um.es
It is thought that the general increase in life expectancy will make osteoarthritis the fourth
leading cause of disability by the year 2020. Even though the pathogenesis of idiopathic …

Pulsed electromagnetic field therapy results in healing of full thickness articular cartilage defect

P Boopalan, S Arumugam, A Livingston… - International …, 2011 - Springer
This study aimed to determine the efficacy of PEMF (pulsed electromagnetic field) treatment
in experimental osteochondral defect healing in a rabbit model. The study was conducted on …

Tonic activation of hypoxia‐inducible factor 1α in avascular articular cartilage and implications for metabolic homeostasis

PU Brucker, NJ Izzo, CR Chu - Arthritis & Rheumatism: Official …, 2005 - Wiley Online Library
Objective To determine whether oxygen‐dependent activation patterns of hypoxia‐inducible
factor 1α (HIF‐1α) observed in vascularized tissues are conserved within avascular and …

Characterization of experimentally induced post-traumatic osteoarthritis in the medial femorotibial joint of horses

CJ Bolam, MB Hurtig, A Cruz… - American journal of …, 2006 - Am Vet Med Assoc
Objective—To study osteoarthritis in the equine medial femorotibial (MFT) joint after a single
traumatic injury. Animals—10 mature horses. Procedure—In vitro explant cultures were used …

The effect of antibody size and mechanical loading on solute diffusion through the articular surface of cartilage

CD DiDomenico, A Goodearl… - Journal of …, 2017 - asmedigitalcollection.asme.org
Because of the heterogeneous nature of articular cartilage tissue, penetration of potential
therapeutic molecules for osteoarthritis (OA) through the articular surface (AS) is complex …

Cyclic mechanical loading enhances transport of antibodies into articular cartilage

CD DiDomenico, Z Xiang Wang… - Journal of …, 2017 - asmedigitalcollection.asme.org
The goal of this study was to characterize antibody penetration through cartilage tissue
under mechanical loading. Mechanical stimulation aids in the penetration of some proteins …