Human glycoprotein of cartilage (YKL-40) synthesises chondrocytes and synovial cells in
inflammatory conditions or remodels the outer cell matrix in osteoarthritis. The aim of this …

The objective was to determine the effects of early exercise on the articular cartilage and
subchondral bone at specific sites of the distal third metacarpal and metatarsal bones of 12 …

Insulin-like growth factor (IGF)-1 is a key factor in bone homeostasis and could be involved
in bone tissue sclerosis as observed in osteoarthritis (OA). Here, we compare the key …

Reactive oxygen species (ROS) are implicated in the pathogenesis of osteoarthritis (OA).
However, little is known about the antioxidant defence system in articular cartilage. We …

OBJECTIVE: Differentiated articular chondrocytes express a functional isoform of the leptin
receptor (LRb); however, leptin-LRb signaling in these cells is poorly understood. We …

There is evidence that vitamin E (VE) has anti-inflammatory and analgesic properties in
human osteoarthritis (OA). This double-blinded and randomized pilot study used a broad …

Objective To test the mechanisms by which adenosine and adenosine analogues stimulate
adenylate cyclase and suppress lipopolysaccharide (LPS)-induced production of nitric oxide …

Objective: A double-blind placebo-controlled randomized study was conducted to assess
the effectiveness of therapeutic ultrasound (US) in knee OA. Patients and Methods: Thirty …

Objective Protein kinase Cζ (PKCζ), an atypical PKC, has been found to be transcriptionally
up‐regulated in human osteoarthritic (OA) articular cartilage. This study was undertaken to …

[Purpose] The purpose of this study was to determine the effect of proprioceptive training on
foot progression angle, weight-bearing ratio, and knee adduction moment in patients with …