MicroRNAs (miRs) are regulatory RNAs with 18–25 nucleotides lengths involved in various
biological processes. Some miRs, including miR-22, play an essential role in regulating …

Background: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative
disease of upper and lower motor neurons with high burden on society. Despite tremendous …

Brain-derived neurotrophic factor (BDNF) is essential for the development and function of
human neurons, therefore it is a promising target for neurodegenerative disorders treatment …

Background. Autologous bone marrow-derived lineage-negative (Lin−) cells present
antiapoptotic and neuroprotective activity. The aim of the study was to evaluate the safety …

Therapeutic interventions in amyotrophic lateral sclerosis (ALS) are still far from satisfying.
Immune modulating procedures raise hopes for slowing the disease progression. Stem cell …

The launch of novel chemotherapeutic agents—in particular, proteasome inhibitors and
immunomodulatory drugs—dramatically changed multiple myeloma (MM) therapy …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease related to the
progressive death of motor neurons. Understanding the pathogenesis of ALS continues to …

MicroRNAs (miRNAs) are the smallest class of noncoding RNAs, which widely exist in
animals and plants. They can inhibit translation or overexpression by combining with mRNA …

Background: Amyotrophic lateral sclerosis (ALS) is an incurable disease. There are vigorous
attempts to develop treatments to reduce the effects of this disease, and among these …

Amyotrophic lateral sclerosis (ALS) remains a fatal, neurodegenerative disease frequently
leading to dysarthria and impaired swallowing. Better understanding of ALS …