Methods for interpreting change over time in patient-reported outcome measures

KW Wyrwich, JM Norquist, WR Lenderking… - Quality of Life …, 2013 - Springer
Purpose Interpretation guidelines are needed for patient-reported outcome (PRO) measures'
change scores to evaluate efficacy of an intervention and to communicate PRO results to …

Asthma outcomes: pulmonary physiology

RS Tepper, RS Wise, R Covar, CG Irvin… - Journal of Allergy and …, 2012 - Elsevier
BACKGROUND: Outcomes of pulmonary physiology have a central place in asthma clinical
research. OBJECTIVE: At the request of National Institutes of Health (NIH) institutes and …

Interpretative strategies for lung function tests

R Pellegrino, G Viegi, V Brusasco… - European respiratory …, 2005 - Eur Respiratory Soc
BACKGROUND This section is written to provide guidance in interpreting pulmonary
function tests (PFTs) to medical directors of hospital-based laboratories that perform PFTs …

Measurement of health status: ascertaining the minimal clinically important difference

R Jaeschke, J Singer, GH Guyatt - Controlled clinical trials, 1989 - Elsevier
In recent years quality of life instruments have been featured as primary outcomes in many
randomized trials. One of the challenges facing the investigator using such measures is …

Espirometría

F García-Río, M Calle, F Burgos, P Casan… - Archivos de …, 2013 - Elsevier
Spirometry is the main pulmonary function test and is essential for the evaluation and
monitoring of respiratory diseases. Its utility transcends the field of Respiratory Medicine, is …

Inhaled bronchodilators reduce dynamic hyperinflation during exercise in patients with chronic obstructive pulmonary disease.

MJ Belman, WC Botnick, JW Shin - American journal of respiratory …, 1996 - atsjournals.org
Dynamic hyperinflation (DH) is a major pathophysiologic consequence of airflow limitation
during exercise in patients with chronic obstructive pulmonary disease (COPD) and an …

Long‐acting beta2‐agonists for poorly reversible chronic obstructive pulmonary disease

S Appleton, P Poole, BJ Smith, A Veale… - Cochrane database …, 2006 - cochranelibrary.com
Background Chronic obstructive pulmonary disease (COPD) is characterised by partially
reversible airflow limitation. Many patients have little reversibility to short acting …

Oral theophylline for chronic obstructive pulmonary disease

FSF Ram, P Jones, J Jardim, AA Castro… - Cochrane database …, 1996 - cochranelibrary.com
Background Oral theophylline has, for many years, been used as a bronchodilator in
patients with COPD. Despite the introduction of new drugs, and its narrow therapeutic index …

Short‐acting beta2‐agonists for stable chronic obstructive pulmonary disease

P Sestini, E Renzoni, S Robinson… - Cochrane Database …, 1996 - cochranelibrary.com
Abstract Background Chronic Obstructive Pulmonary Disease (COPD) is a chronic condition
characterised by progressive airflow limitation that is at most partially reversible. Despite the …

Bronchopulmonary disease in the cat: historical, physical, radiographic, clinicopathologic, and pulmonary functional evaluation of 24 affected and 15 healthy cats

JA Dye, BC McKiernan, EA Rozanski… - Journal of Veterinary …, 1996 - Wiley Online Library
The results of clinical and pulmonary functional evaluation of 24 cats with
bronchopulmonary disease and 15 healthy cats are presented. Affected cats had historical …