Efficacy and safety of dietary therapies for childhood drug-resistant epilepsy: a systematic review and network meta-analysis

N Devi, P Madaan, N Kandoth, D Bansal… - JAMA …, 2023 - jamanetwork.com
Importance Despite advances in the understanding of dietary therapies in children with drug-
resistant epilepsy, no quantitative comparison exists between different dietary interventions …

Current and emerging pharmacotherapy for the treatment of Lennox-Gastaut syndrome

FMC Besag, MJ Vasey, RFM Chin - Expert Opinion on …, 2023 - Taylor & Francis
ABSTRACT Introduction Lennox-Gastaut syndrome (LGS) is a severe childhood-onset
epileptic encephalopathy, characterized by multiple seizure types, generalized slow spike …

[HTML][HTML] Cannabidiol inhibits microglia activation and mitigates neuronal damage induced by kainate in an in-vitro seizure model

E Landucci, C Mazzantini, D Lana, M Calvani… - Neurobiology of …, 2022 - Elsevier
Background Epilepsy is one of the most common brain disorder and, despite the possible
use of several therapeutic options, many patients continue to have seizures for their entire …

[HTML][HTML] Therapeutic efficacy of voltage-gated sodium channel inhibitors in epilepsy

J Agbo, ZG Ibrahim, SY Magaji, YB Mutalub… - Acta Epileptologica, 2023 - Springer
Epilepsy is a neurological disease characterized by excessive and abnormal hyper-
synchrony of electrical discharges of the brain and a predisposition to generate epileptic …

Evaluating fenfluramine hydrochloride as an oral solution for the treatment of seizures associated with Lennox-Gastaut syndrome

FMC Besag, MJ Vasey, RFM Chin - Expert review of …, 2024 - Taylor & Francis
ABSTRACT Introduction Lennox-Gastaut syndrome (LGS) is a severe childhood-onset
developmental and epileptic encephalopathy characterized by treatment-refractory seizures …

CBD in the Treatment of Epilepsy

K Borowicz-Reutt, J Czernia, M Krawczyk - Molecules, 2024 - mdpi.com
It has been several years since highly purified cannabidiol (CBD) was registered as a
medication that can be used in children of at least 2 years of age to treat different types of …

[HTML][HTML] Factors associated with long-term benzodiazepine and Z-drug use across the lifespan and 5-year temporal trajectories among incident users: a Swedish …

K Isomura, X Wang, Z Chang, C Hellner… - European Journal of …, 2023 - Springer
Purpose Despite being discouraged by guidelines, long-term use of benzodiazepines and
related Z-drugs (BZDR) remains frequent in the real-world. An improved understanding of …

氯巴占与大麻二酚辅助治疗Lennox-Gastaut 综合征新进展

石静天, 陈超阳, 杨婷, 魏然, 张玄龄, 王梓凝, 胡晓娟… - 罕见病研究, 2024 - jrd.chard.org.cn
Lennox-Gastaut 综合征(LGS) 是一种严重的癫痫性脑病. 近年来, 已有多种药物被批准用于治疗
LGS. 美国食品药品监督管理局分别于2011 年10 月和2018 年6 月批准了氯巴占 …

[引用][C] Side effects of antiseizure medications

D Greer, MT Liu, M Maroney - 2023 - Elsevier