Background: An ENDO-European Reference Network (ERN) initiative was launched that
was endorsed by the European Society for Pediatric Endocrinology and the European …

Central congenital hypothyroidism (CH) is defined as thyroid hormone (TH) deficiency at
birth due to insufficient stimulation by the pituitary of the thyroid gland. The incidence of …

Objectives: Central hypothyroidism (CeH) is a rare form of hypothyroidism characterized by
insufficient thyroid stimulation due to disturbed pituitary and/or hypothalamic functioning …

Untreated congenital hypothyroidism (CH) leads to intellectual disabilities. Prompt diagnosis
by newborn screening (NBS) leading to early and adequate treatment results in grossly …

Prompt identification and adequate treatment of patients with congenital hypothyroidism is
critical to optimize outcomes. New information continues to accumulate about how to …

The evaluation and management of hypothyroidism in children are similar to adults, but
there are important differences based on the dependence on normal thyroid function for …

Background Neonatal screening in Germany currently comprises 19 congenital diseases, 13
of which are metabolic diseases. Approximately one in 1300 newborns suffers from one of …

Central hypothyrodism (CeH) is a hypothyroid state caused by an insufficient stimulation by
thyrotropin (TSH) of an otherwise normal thyroid gland. Several advancements, including …

Purpose of developing the guidelines: Newborn screening (NBS) for congenital
hypothyroidism (CH) was started in 1979 in Japan, and early diagnosis and treatment …

Congenital hypothyroidism (CH) is a relatively frequent congenital endocrine disorder,
caused by defective production of thyroid hormones (THs) at birth. Because THs are …