Context Subtle cognitive impairments have been described in children with congenital
hypothyroidism (CH) detected by neonatal screening (NS), even with early and adequate …

Objective To provide an overview of cognitive and motor outcome, and quality of life (QoL) in
patients with congenital central hypothyroidism (CH-C). Design Systematic review with …

Background: Congenital hypothyroidism (CH) is a common and preventable cause of mental
retardation, which is detected in many neonatal screening programs. Upon suspicion of CH …

Objectives: Identify the etiology of congenital hypothyroidism. Describe the signs and
symptoms of congenital hypothyroidism. Review the newborn screening and thyroid function …

Context Early treatment of primary congenital hypothyroidism (CH) prevents irreversible
brain damage. Contrary to primary CH, outcome studies on central CH are scarce. Most …

This study assessed white matter microstructural integrity and behavioral correlates for
children with severe congenital hypothyroidism (CH) who were identified and treated early …

Objectives We designed a multicentre open prospective randomized trial to evaluate the risk-
benefit profile of two different initial treatment schemes with levothyroxine (L-T4), 10-12.5 …

Objectives: To describe the neurocognitive profile of 458 children with congenital
hypothyroidism detected by neonatal screening, followed under the same treatment protocol …

Context Patients with congenital hypothyroidism (CH) are affected more often than the
general population by other chronic diseases and neurological difficulties. Objective The …

Objective Oral solution and tablet formulations of levothyroxine (L-T4) are both used in the
treatment of congenital hypothyroidism (CH). However, few studies and with a limited follow …