Cycles in epilepsy

PJ Karoly, VR Rao, NM Gregg, GA Worrell… - Nature Reviews …, 2021 - nature.com
Epilepsy is among the most dynamic disorders in neurology. A canonical view holds that
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …

Sleep and epilepsy: A snapshot of knowledge and future research lines

L Nobili, B Frauscher, S Eriksson… - Journal of sleep …, 2022 - Wiley Online Library
Sleep and epilepsy have a reciprocal relationship, and have been recognized as bedfellows
since antiquity. However, research on this topic has made a big step forward only in recent …

[HTML][HTML] Sleep and epilepsy: a focused review of pathophysiology, clinical syndromes, co-morbidities, and therapy

JL Moore, DZ Carvalho, EK St Louis, C Bazil - Neurotherapeutics, 2021 - Elsevier
A healthy brain requires balancing of waking and sleeping states. The normal changes in
waking and sleeping states result in neurophysiological conditions that either increase or …

[HTML][HTML] Epilepsy and its interaction with sleep and circadian rhythm

B Jin, T Aung, Y Geng, S Wang - Frontiers in Neurology, 2020 - frontiersin.org
Growing evidence shows the bidirectional interactions between sleep, circadian rhythm, and
epilepsy. Comprehending how these interact with each other may help to advance our …

[HTML][HTML] Low-dose perampanel rescues cortical gamma dysregulation associated with parvalbumin interneuron GluA2 upregulation in epileptic Syngap1+/− mice

BJ Sullivan, S Ammanuel, PA Kipnis, Y Araki… - Biological …, 2020 - Elsevier
Background Loss-of-function SYNGAP1 mutations cause a neurodevelopmental disorder
characterized by intellectual disability and epilepsy. SYNGAP1 is a Ras GTPase-activating …

Sleep quality and related clinical features in patients with epilepsy: a preliminary report

AE Çilliler, B Güven - Epilepsy & Behavior, 2020 - Elsevier
Objective The relationship between sleep and epilepsy is complex and involves multiple
mechanisms. Patients with epilepsy (PWE) often report fatigue and daytime sleepiness, and …

[HTML][HTML] Rapid eye movement sleep reduction in patients with epilepsy: A systematic review and meta-analysis

WC Yeh, HJ Lin, YS Li, CF Chien, MN Wu, LM Liou… - Seizure, 2022 - Elsevier
Background: Compared to healthy controls, adults with epilepsy have a disrupted sleep
architecture. Changes in sleep macrostructure may be associated with the refractoriness of …

Sleep and epilepsy, clinical spectrum and updated review

T Wu, AY Avidan, J Engel - Sleep medicine clinics, 2021 - sleep.theclinics.com
Recording of brain wave patterns during sleep often is essential in the evaluation of patients
presenting for complex nocturnal behaviors. It is helpful particularly when sleep-related …

Outpatient visit behavior in patients with epilepsy: Generalized Epilepsy is more frequently non-attendance than Focal Epilepsy

Y Nakamura, K Sakurai, S Ishikawa, T Horinouchi… - Epilepsy & Behavior, 2023 - Elsevier
Background Patients with epilepsy (PWE), especially those with Idiopathic Epilepsy (GE),
are at a high risk of disadvantage caused by non-adherence. It has been suggested that …

Sleep deprivation exacerbates concussive head injury induced brain pathology: Neuroprotective effects of nanowired delivery of cerebrolysin with α-melanocyte …

A Sharma, DF Muresanu, A Ozkizilcik, ZR Tian… - Progress in brain …, 2019 - Elsevier
Sleep deprivation (SD) is very common in military personnel resulting in mental anomalies
and interfering with decision-making capabilities. Moreover during combat operation, these …