Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management

JS Knight, DW Branch, TL Ortel - bmj, 2023 - bmj.com
Antiphospholipid syndrome (APS) is a thrombo-inflammatory disease propelled by
circulating autoantibodies that recognize cell surface phospholipids and phospholipid …

The antiphospholipid syndrome in patients with systemic lupus erythematosus

GJ Pons-Estel, L Andreoli, F Scanzi, R Cervera… - Journal of …, 2017 - Elsevier
The antiphospholipid syndrome (APS) is an autoimmune disease characterized by the
occurrence of venous and/or arterial thrombosis and pregnancy morbidity in the presence of …

EULAR recommendations for the management of antiphospholipid syndrome in adults

MG Tektonidou, L Andreoli, M Limper… - Annals of the …, 2019 - ard.bmj.com
The objective was to develop evidence-based recommendations for the management of
antiphospholipid syndrome (APS) in adults. Based on evidence from a systematic literature …

Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association

JF Meschia, C Bushnell, B Boden-Albala, LT Braun… - Stroke, 2014 - Am Heart Assoc
The aim of this updated statement is to provide comprehensive and timely evidence-based
recommendations on the prevention of stroke among individuals who have not previously …

[HTML][HTML] Thrombophilia testing: a British Society for Haematology guideline

DJ Arachchillage, L Mackillop… - British journal of …, 2022 - ncbi.nlm.nih.gov
Guidelines Committee and the sounding board of BSH. It was also placed on the members
section of the BSH website for comment. It has also been reviewed by Royal College of …

Incidence of a first thromboembolic event in asymptomatic carriers of high-risk antiphospholipid antibody profile: a multicenter prospective study

V Pengo, A Ruffatti, C Legnani, S Testa… - Blood, The Journal …, 2011 - ashpublications.org
Persistent antiphospholipid (aPL) antibodies are occasionally found in subjects without prior
history of thromboembolic events (TEs), raising the dilemma of whether to initiate or not a …

The effect of hydroxychloroquine on thrombosis prevention and antiphospholipid antibody levels in primary antiphospholipid syndrome: a pilot open label randomized …

E Kravvariti, A Koutsogianni, E Samoli, PP Sfikakis… - Autoimmunity …, 2020 - Elsevier
Background Sporadic studies suggest hydroxychloroquine (HCQ) may be effective for
thrombosis prevention in patients with primary antiphospholipid syndrome (PAPS) and may …

Efficacy of aspirin for the primary prevention of thrombosis in patients with antiphospholipid antibodies: an international and collaborative meta-analysis

L Arnaud, A Mathian, A Ruffatti, D Erkan… - Autoimmunity …, 2014 - Elsevier
We performed a meta-analysis to determine whether aspirin has a significant protective
effect on risk of first thrombosis among patients with antiphospholipid antibodies (aPL+) …

Pathogenesis and management of antiphospholipid syndrome

DRJ Arachchillage, M Laffan - British journal of haematology, 2017 - Wiley Online Library
Antiphospholipid antibodies are a heterogeneous group of autoantibodies that have clear
associations with thrombosis and pregnancy morbidity, and which together constitute the …

Antiphospholipid syndrome–an update

B Linnemann - Vasa, 2018 - econtent.hogrefe.com
Antiphospholipid syndrome (APS) is an autoantibody-mediated acquired thrombophilia. It is
characterized by the presence of antiphospholipid antibodies (APL) that are directed against …