A thrombin-driven neural net diagnoses the antiphospholipid syndrome without the need for interruption of anticoagulation

RMW de Laat-Kremers, D Wahl, S Zuily… - Blood …, 2024 - ashpublications.org
Thrombosis is an important manifestation of the antiphospholipid syndrome (APS). The
thrombin generation (TG) test is a global hemostasis assay, and increased TG is associated …

Antiphospholipid antibody testing for anti-cardiolipin and anti-β2 glycoprotein I antibodies using chemiluminescence-based panels

EJ Favaloro, S Mohammed, R Vong… - … and Thrombosis: Methods …, 2023 - Springer
Abstract Antiphospholipid (antibody) syndrome (APS) is a prothrombotic condition with
increased risk for thrombosis and pregnancy-related morbidity. In addition to clinical criteria …

Towards harmonized interpretation of anticardiolipin and anti-β2-glycoprotein I antibody detection for diagnosis of antiphospholipid syndrome using defined level …

A Vandevelde, JC Gris, GW Moore, J Musiał… - Journal of Thrombosis …, 2024 - Elsevier
Background Improving harmonization of the clinical interpretation of anticardiolipin (aCL)
and anti-β2-glycoprotein I antibodies (aβ2GPI) IgG/IgM in the diagnosis of antiphospholipid …

Measurement of lupus anticoagulants: an update on quality in laboratory testing

M Adams - Seminars in thrombosis and hemostasis, 2013 - thieme-connect.com
Lupus anticoagulants (LAs) are antiphospholipid antibodies that interfere with in vitro
phospholipid-dependent clotting tests, but are associated in vivo with significant clinical …

Anti-phospholipid antibodies and smoking: an overview

SR Binder, CM Litwin - Clinical Reviews in Allergy & Immunology, 2017 - Springer
Antiphospholipid syndrome is characterized by the presence of antiphospholipid antibodies,
specifically lupus anticoagulant, anticardiolipin antibodies, and anti-β2 glycoprotein-I …

Thrombotic risk in the antiphospholipid syndrome

W Lim - Seminars in thrombosis and hemostasis, 2014 - thieme-connect.com
The antiphospholipid syndrome (APS) is characterized by venous or arterial thrombosis
and/or pregnancy morbidity in patients with persistent presence of antiphospholipid …

Regulation in hemostasis and thrombosis: part I—in vitro diagnostics

EJ Favaloro, M Plebani, G Lippi - Seminars in thrombosis and …, 2013 - thieme-connect.com
The diagnostic or test-performance process, as associated to the evaluation or diagnosis of
hemostasis and thrombosis and related disorders, is influenced or controlled by the activity …

[HTML][HTML] The impact of repeated freeze‐thaw cycles on antiphospholipid antibody titer

K Maelegheer, KMJ Devreese - Research and Practice in Thrombosis and …, 2018 - Elsevier
Essentials• Limited data are available of freeze‐thaw effect on anticardiolipin and anti‐beta2‐
glycoprotein I antibodies.• Patient samples with antibody titer over a broad range were …

Trials and tribulations in lupus anticoagulant testing

EJ Favaloro - Clinical Chemistry and Laboratory Medicine (CCLM), 2013 - degruyter.com
This issue of Clinical Chemistry and Laboratory Medicine includes a report by Pradella and
colleagues regarding a cooperative multicentre study to define the upper limits of normal for …

Antiphospholipid antibodies and the antiphospholipid syndrome: from coagulation to the clinic

R Selby, J Abdulrehman - The Journal of Applied Laboratory …, 2022 - academic.oup.com
Antiphospholipid syndrome (APS) is a systemic, autoimmune disorder characterized by the
presence of antiphospholipid antibodies (APLA) directed to various plasma proteins bound …