Background The targeting accuracy of proton therapy (PT) for moving soft-tissue tumours is
expected to greatly improve by real-time magnetic resonance imaging (MRI) guidance. The …

Featured Application Radiation therapy treatment planning. Abstract Radiation therapy (RT)
is a constantly evolving therapeutic technique; improvements are continuously being …

In this review article, we review the 3 important aspects of linear-energy-transfer (LET) in
intensity-modulated proton therapy (IMPT) for head and neck (H&N) cancer management …

Arc proton therapy (ArcPT) is an emerging modality in cancer treatments. It delivers the
proton beams following a sequence of irradiation angles while the gantry is continuously …

Purpose The purpose of this study was to address the dosimetric accuracy of synthetic
computed tomography (sCT) images of patients with brain tumor generated using a modified …

The relative biological effectiveness (RBE) of protons is highly variable and difficult to
quantify. However, RBE is related to the local ionization density, which can be related to the …

Purpose To develop an online graphic processing unit (GPU)‐accelerated Monte Carlo‐
based adaptive radiation therapy (ART) workflow for pencil beam scanning (PBS) proton …

Monte Carlo (MC)‐based dose calculations are generally superior to analytical dose
calculations (ADC) in modeling the dose distribution for proton pencil beam scanning (PBS) …

Purpose To commission an open source Monte Carlo (MC) dose engine,“MCsquare” for a
synchrotron‐based proton machine, integrate it into our in‐house C++‐based I/O user …

Objective. Next generation online and real-time adaptive radiotherapy workflows require
precise particle transport simulations in sub-second times, which is unfeasible with current …