Dietary polyphenols: Regulate the advanced glycation end products-RAGE axis and the microbiota-gut-brain axis to prevent neurodegenerative diseases

Y Li, Y Peng, Y Shen, Y Zhang, L Liu… - Critical Reviews in Food …, 2023 - Taylor & Francis
Advanced glycation end products (AGEs) are formed in non-enzymatic reaction, oxidation,
rearrangement and cross-linking between the active carbonyl groups of reducing sugars …

Drugs in clinical trials for Alzheimer's disease: the major trends

SO Bachurin, EV Bovina… - Medicinal research …, 2017 - Wiley Online Library
Alzheimer's disease (AD) is characterized by a chronic and progressive neurodegenerative
process resulting from the intracellular and extracellular accumulation of fibrillary proteins …

Current research therapeutic strategies for Alzheimer's disease treatment

J Folch, D Petrov, M Ettcheto, S Abad… - Neural …, 2016 - Wiley Online Library
Alzheimer's disease (AD) currently presents one of the biggest healthcare issues in the
developed countries. There is no effective treatment capable of slowing down disease …

Monoaminergic neuropathology in Alzheimer's disease

G Šimić, MB Leko, S Wray, CR Harrington… - Progress in …, 2017 - Elsevier
None of the proposed mechanisms of Alzheimer's disease (AD) fully explains the distribution
patterns of the neuropathological changes at the cellular and regional levels, and their …

[HTML][HTML] The serotonergic system and cognitive function

D Švob Štrac, N Pivac, D Mück-Šeler - Translational neuroscience, 2016 - degruyter.com
Symptoms of cognitive dysfunction like memory loss, poor concentration, impaired learning
and executive functions are characteristic features of both schizophrenia and Alzheimer's …

[HTML][HTML] Mechanism of quercetin therapeutic targets for Alzheimer disease and type 2 diabetes mellitus

G Zu, K Sun, L Li, X Zu, T Han, H Huang - Scientific reports, 2021 - nature.com
Quercetin has demonstrated antioxidant, anti-inflammatory, hypoglycemic, and
hypolipidemic activities, suggesting therapeutic potential against type 2 diabetes mellitus …

Neuroanatomy and pathology of sporadic Alzheimer's disease

H Braak, K Del Tredici - 2014 - books.google.com
As indicated by its title, this monograph deals chiefly with morphologically recognizable
deviations from the normal anatomical condition of the human CNS. The AD-associated …

[HTML][HTML] Multiple roles of fucoxanthin and astaxanthin against Alzheimer's disease: Their pharmacological potential and therapeutic insights

N Oliyaei, M Moosavi-Nasab, N Tanideh, A Iraji - Brain Research Bulletin, 2023 - Elsevier
Alzheimer's disease (AD) is the most devastating neurodegenerative disorder affecting the
elderly. The exact pathology of AD is not yet fully understood and several hallmarks such as …

Lactobacillus probiotics improved the gut microbiota profile of a Drosophila melanogaster Alzheimer's disease model and alleviated neurodegeneration in the eye

FHP Tan, G Liu, SYA Lau, MH Jaafar… - Beneficial …, 2020 - wageningenacademic.com
Alzheimer's disease (AD) is a progressive disease and one of the most common forms of
neurodegenerative disorders. Emerging evidence is supporting the use of various strategies …

Diagnosis and management of neuropsychiatric symptoms in Alzheimer's disease

D Wolinsky, K Drake, J Bostwick - Current psychiatry reports, 2018 - Springer
Abstract Purpose of Review To explore the most recent developments in the effective
diagnosis and treatment of neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) …