Hyaluronic acid: A key ingredient in the therapy of inflammation

A Marinho, C Nunes, S Reis - Biomolecules, 2021 - mdpi.com
Hyaluronic acid (HA) is a natural polymer, produced endogenously by the human body,
which has unique physicochemical and biological properties, exhibiting desirable …

[HTML][HTML] Hyaluronic acid and its biomedical applications: A review

M Dovedytis, ZJ Liu, S Bartlett - Engineered Regeneration, 2020 - Elsevier
Hyaluronic acid is a naturally occurring biopolymer possessing numerous functions within
the body including wound repair, cell migration, and cell signaling. Due to its versatility …

Myofibroblasts: function, formation, and scope of molecular therapies for skin fibrosis

Y Tai, EL Woods, J Dally, D Kong, R Steadman… - Biomolecules, 2021 - mdpi.com
Myofibroblasts are contractile, α-smooth muscle actin-positive cells with multiple roles in
pathophysiological processes. Myofibroblasts mediate wound contractions, but their …

Glycosaminoglycan–protein interactions: the first draft of the glycosaminoglycan interactome

SD Vallet, O Clerc… - Journal of Histochemistry …, 2021 - journals.sagepub.com
The six mammalian glycosaminoglycans (GAGs), chondroitin sulfate, dermatan sulfate,
heparin, heparan sulfate, hyaluronan, and keratan sulfate, are linear polysaccharides …

Hyaluronan biology: A complex balancing act of structure, function, location and context

S Garantziotis, RC Savani - Matrix Biology, 2019 - Elsevier
Cell-matrix interactions are fundamental to many developmental, homeostatic, immune and
pathologic processes. Hyaluronan (HA), a critical component of the extracellular matrix …

Dermal extracellular matrix molecules in skin development, homeostasis, wound regeneration and diseases

J Huang, S Heng, W Zhang, Y Liu, T Xia, C Ji… - Seminars in Cell & …, 2022 - Elsevier
The extracellular matrix (ECM) is a dynamic structure that surrounds and anchors cellular
components in tissues. In addition to functioning as a structural scaffold for cellular …

Comprehensive review on biotechnological production of hyaluronic acid: status, innovation, market and applications

R Ucm, M Aem, Z Lhb, V Kumar, MJ Taherzadeh… - …, 2022 - Taylor & Francis
The growing, existing demand for low-cost and high-quality hyaluronic acid (HA) needs an
outlook of different possible production strategies from renewable resources with the …

Hyaluronic acid: known for almost a century, but still in vogue

A Lierova, J Kasparova, A Filipova, J Cizkova… - Pharmaceutics, 2022 - mdpi.com
Hyaluronic acid (HA) has a special position among glycosaminoglycans. As a major
component of the extracellular matrix (ECM). This simple, unbranched polysaccharide is …

[HTML][HTML] The role of the ECM in lung cancer dormancy and outgrowth

AL Parker, TR Cox - Frontiers in oncology, 2020 - frontiersin.org
The dissemination of tumor cells to local and distant sites presents a significant challenge in
the clinical management of many solid tumors. These cells may remain dormant for months …

Proposed mechanisms of targeting COVID-19 by delivering mesenchymal stem cells and their exosomes to damaged organs

E Jamshidi, A Babajani, P Soltani… - Stem Cell Reviews and …, 2021 - Springer
With the outbreak of coronavirus disease (COVID-19) caused by novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), the world has been facing an …