From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology

A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

When does acute pain become chronic?

C Voscopoulos, M Lema - British journal of anaesthesia, 2010 - academic.oup.com
The transition from acute to chronic pain appears to occur in discrete pathophysiological and
histopathological steps. Stimuli initiating a nociceptive response vary, but receptors and …

An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids …

JP Huggins, TS Smart, S Langman, L Taylor, T Young - PAIN®, 2012 - Elsevier
The effect of PF-04457845, a potent and selective fatty acid amide hydrolase-1 (FAAH1)
inhibitor, on pain due to osteoarthritis of the knee was investigated in a randomised placebo …

[图书][B] Psychology and life

RJ Gerrig, PG Zimbardo, AJ Campbell, SR Cumming… - 2015 - books.google.com
Bringing the science of psychology to life! The 2nd Australasian edition of Psychology and
Life emphasises the science of psychology, with a special focus on applying that science to …

The clinical aspects of mirror therapy in rehabilitation: a systematic review of the literature

AS Rothgangel, SM Braun, AJ Beurskens… - International Journal …, 2011 - journals.lww.com
The objective of this study was to evaluate the clinical aspects of mirror therapy (MT)
interventions after stroke, phantom limb pain and complex regional pain syndrome. A …

Opportunities for cannabis in supportive care in cancer

AS Kleckner, IR Kleckner, CS Kamen… - … in medical oncology, 2019 - journals.sagepub.com
Cannabis has the potential to modulate some of the most common and debilitating
symptoms of cancer and its treatments, including nausea and vomiting, loss of appetite, and …

Rapid assessment of a novel series of selective CB2 agonists using parallel synthesis protocols: A Lipophilic Efficiency (LipE) analysis

T Ryckmans, MP Edwards, VA Horne… - Bioorganic & medicinal …, 2009 - Elsevier
A series of libraries were designed using the 1-(cyclopropylmethyl)-2-alkyl-4, 5, 6, 7-
tetrahydro-1H-imidazo [4, 5-c] pyridin-5-ium templates 2a–b, and Sulfonamide derivatives …

Cannabinoid signaling in health and disease

Y Lu, HD Anderson - Canadian journal of physiology and …, 2017 - cdnsciencepub.com
Cannabis sativa has long been used for medicinal purposes. To improve safety and efficacy,
compounds from C. sativa were purified or synthesized and named under an umbrella group …

Aspectos básicos del dolor postoperatorio y la analgesia multimodal preventiva

J Rosa-Díaz, V Navarrete-Zuazo… - Revista mexicana de …, 2014 - medigraphic.com
El dolor postoperatorio no cumple una función útil y el peligro de no tratarlo es que aumenta
la morbimortalidad postoperatoria. Su tratamiento satisfactorio es uno de los retos más …

The medical necessity for medicinal cannabis: prospective, observational study evaluating the treatment in cancer patients on supportive or palliative care

G Bar-Sela, M Vorobeichik, S Drawsheh… - Evidence‐Based …, 2013 - Wiley Online Library
Background. Cancer patients using cannabis report better influence from the plant extract
than from synthetic products. However, almost all the research conducted to date has been …