[HTML][HTML] The emerging risk of microplastics and nanoplastics on the microstructure and function of reproductive organs in mammals: A systematic review of preclinical …

RC Marcelino, RM Cardoso, ELBC Domingues… - Life Sciences, 2022 - Elsevier
Aims Plastic particles (PP) pollution is a global environmental concern. Although the
reproductive toxicity of PP is primarily understood for invertebrates, the evidence for …

[HTML][HTML] Impact of microplastics on the intestinal microbiota: A systematic review of preclinical evidence

TG de Souza-Silva, IA Oliveira, GG da Silva, FCV Giusti… - Life sciences, 2022 - Elsevier
Aims We systematically review the in vivo preclinical evidence on the impact of microplastics
(MPs) on the intestinal microbiota and morphofunctional changes involving the intestinal …

Animal models of Chagas disease and their translational value to drug development

E Chatelain, I Scandale - Expert Opinion on Drug Discovery, 2020 - Taylor & Francis
Introduction American trypanosomiasis, better known as Chagas disease, is a global public
health issue. Current treatments targeting the causative parasite, Trypanosoma cruzi, are …

[PDF][PDF] Antifungal, antibacterial and antioxidant components of ethyl acetate extract of quinoa stem

IH Khan, A Javaid - Plant Protection, 2019 - academia.edu
The use of plant products is an old-age practice for the treatment of infectious diseases and
pathogens. Interest in plant products has been revived again due to the hazardous effects of …

Effects of the amount and type of carbohydrates used in type 2 diabetes diets in animal models: A systematic review

AM Marques, BS Linhares, R Dias Novaes, MB Freitas… - PloS one, 2020 - journals.plos.org
Type 2 diabetes mellitus (T2DM) is among the most prevalent diseases in the world,
affecting over 420 million people. The disease is marked by a poor metabolic effect of insulin …

Monotherapy and combination chemotherapy for Chagas disease treatment: A systematic review of clinical efficacy and safety based on randomized controlled trials

SS Nogueira, EC Santos, RO Silva, RV Gonçalves… - Parasitology, 2022 - cambridge.org
From a systematic review framework, we analysed the clinical evidence on the effectiveness
and safety of monotherapy and combination chemotherapy for Chagas disease (ChD) …

Nanotechnology enabled the enhancement of antitrypanosomal activity of piperine against Trypanosoma evansi

R Rani, S Kumar, N Dilbaghi, R Kumar - Experimental Parasitology, 2020 - Elsevier
Nanoencapsulation is the promising approach to enhance the therapeutic potential of a
drug. In the present investigation, piperine-loaded nanocapsules (NCs) was prepared and …

A scoping review on efficacy and safety of medicinal plants used for the treatment of diarrhea in sub-Saharan Africa

MTA Plaatjie, TGE Onyiche, T Ramatla… - Tropical Medicine and …, 2024 - Springer
Abstract Background In sub-Saharan Africa (SSA), significant morbidity and mortality have
been linked to diarrhea, which is frequently caused by microorganisms. A rise in …

Challenges of immunosuppressive and antitrypanosomal drug therapy after heart transplantation in patients with chronic Chagas disease: a systematic review of …

SS Nogueira, AA Felizardo, IS Caldas… - Transplantation …, 2018 - Elsevier
Background Although contraindicated for decades, heart transplantation (HT) has finally
become a feasible therapeutic option for the treatment of Chagasic patients with end-stage …

[HTML][HTML] Microalgae extracts: Potential anti-Trypanosoma cruzi agents?

R Veas, M Rojas-Pirela, C Castillo, C Olea-Azar… - Biomedicine & …, 2020 - Elsevier
Introduction Chagas disease, caused by the protozoan parasiteTrypanosoma cruzi, has no
effective treatment available. On the other hand, microalgae are aquatic organisms that …