PGD for adult-onset conditions is ethically justified when the condition is serious and no
safe, effective interventions are available. It is ethically allowed for conditions of lesser …

Preimplantation genetic testing (PGT) involves testing embryos created through in vitro
fertilization for the presence of hereditary genetic disorders and chromosome abnormalities …

Despite no consensus on the definition of 'seriousness', the concept is regularly used in
policy and practice contexts to categorise conditions, determine access to genetic …

Women who test positive for a BRCA genetic mutation are at an increased risk for
developing hereditary breast and ovarian cancer and have a 50% chance of passing on …

Despite research on BRCA1/2 mutation carriers attitudes towards preimplantation genetic
diagnosis (PGD), considerably less is known about individuals' experience with its use …

Prenatal diagnosis (PND) and preimplantation genetic diagnosis (PGD) for later onset
and/or reduced penetrance inherited cancer predispositions, eg familial adenomatous …

Building on seminal studies of the last 20 years, genetic testing for hypertrophic
cardiomyopathy (HCM) has become a clinical reality in the form of targeted exonic …

Highlights•Various indications for PGD are available. The indications for PGD have
expanded from early–onset, serious diseases to the more controversial late-onset …

The use of PGD technology to select against genetic disorders and traits is increasing.
Although PGD may eliminate some of the obstacles related to conservative options of …

This study examined perspectives on the ethical implications of preimplantation genetic
testing (PGT) among individuals who actually (not hypothetically) used or considered using …