Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey

R Kones - Drug design, development and therapy, 2011 - Taylor & Francis
A recent explosion in the amount of cardiovascular risk and incipient, undetected subclinical
cardiovascular pathology has swept across the globe. Nearly 70% of adult Americans are …

Cholesterol metabolism in CKD

AB Reiss, I Voloshyna, J De Leon, N Miyawaki… - American Journal of …, 2015 - Elsevier
Patients with chronic kidney disease (CKD) have a substantial risk of developing coronary
artery disease. Traditional cardiovascular disease (CVD) risk factors such as hypertension …

Lipids and lipoproteins and risk of different vascular events in the MRC/BHF Heart Protection Study

S Parish, A Offer, R Clarke, JC Hopewell, MR Hill… - Circulation, 2012 - Am Heart Assoc
Background—Low-density lipoprotein (LDL) cholesterol and high-density lipoprotein (HDL)
cholesterol are established risk factors for vascular disease, but lipoprotein particle …

Myeloperoxidase-derived oxidants modify apolipoprotein AI and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with …

KA Hadfield, DI Pattison, BE Brown, L Hou… - Biochemical …, 2013 - portlandpress.com
Oxidative modification of HDLs (high-density lipoproteins) by MPO (myeloperoxidase)
compromises its anti-atherogenic properties, which may contribute to the development of …

HDL anti-oxidant function associates with LDL level in young adults

CV Breton, F Yin, X Wang, E Avol, FD Gilliland… - Atherosclerosis, 2014 - Elsevier
Objectives The primary objective was to evaluate predictors of HDL anti-oxidant function in
young adults. Background High-density lipoprotein (HDL) cholesterol is considered a …

Impact of lifestyle intervention on HDL‐induced eNOS activation and cholesterol efflux capacity in obese adolescent

J Wesnigk, L Bruyndonckx, VY Hoymans… - Cardiology research …, 2016 - Wiley Online Library
Background. Endothelial dysfunction occurs in obese children and adolescent and is
regarded as a key step in the development of atherosclerosis. Important components for the …

Proteome profiles of HDL particles of patients with chronic heart failure are associated with immune response and also include bacteria proteins

A Oberbach, V Adams, N Schlichting, M Heinrich… - Clinica chimica acta, 2016 - Elsevier
Besides modulation of reverse cholesterol transport, high density lipoprotein (HDL) is able to
modulate vascular function by stimulating endothelial nitric oxide synthase. Recently, it …

Cardiovascular disease in south asian immigrants: a review of dysfunctional HDL as a potential marker

R Dod, A Rajendran, M Kathrotia, A Clarke… - Journal of racial and …, 2023 - Springer
Abstract South Asians (SAs) account for a quarter of the world's population and are one of
the fastest-growing immigrant groups in the United States (US). South Asian Immigrants …

Dysfunctional HDL: the journey from savior to slayer

C Serban, D Muntean, DP Mikhailids… - Clinical Lipidology …, 2014 - search.proquest.com
HDL has many functions such as reverse cholesterol transport, anti-inflammation and
antioxidation. Different clinical conditions associated with inflammation, oxidation, advanced …

Cuban Sugar Cane Wax Acid and Policosanol Showed Similar Atheroprotective Effects with Inhibition of LDL Oxidation and Cholesteryl Ester Transfer via …

KH Cho, MA Bae, JR Kim - Cardiovascular Therapeutics, 2019 - Wiley Online Library
Background. Cuban sugarcane wax acids (SCWA) and policosanol (PCO) are mixtures of
higher aliphatic acids and alcohols, respectively, purified from sugarcane wax with different …