Pain is one of the classical signs of the inflammatory process in which sensitization of the
nociceptors is the common denominator. This sensitization causes hyperalgesia or allodynia …

The prevalence of immunoglobulin E (IgE)‐mediated allergic diseases has been increasing
for the last four decades. In this review determinants for an increased IgE synthesis are …

This third edition is an update on every conceivable aspect of the modern-day management
of contact dermatitis. Both irritant and allergic contact dermatitis are covered clearly and …

Wound healing is an integrated and complex process involving a large number of regulatory
molecules, including proinflammatory cytokines and growth factors, and an orchestrated …

Numerous inflammatory cytokines and growth factors have been identified and are known to
be essential for normal wound healing and host defense, and many have been implicated in …

Wound healing requires a complex series of reactions and interactions among cells and
their mediators, resulting in an overlapping series of events including coagulation …

Allergenicity depends on several factors determined by the very physicochemical nature of
the molecules themselves, ie, their capacity to penetrate the horny layer, lipophilicity, and …

Several studies have established a role for interferon beta (IFNβ) as a treatment for
relapsing–remitting multiple sclerosis (MS). IFNβ has been reported to decrease the relapse …

Purpose: Adult cancer is frequently preceded by a period of prolonged chronic inflammation
caused by infectious microbial agents or physical or chemical irritants. By contrast, an …

Contact dermatitis describes the skin reaction resulting from exposure to irritants (irritant
contact dermatitis) or allergens (allergic contact dermatitis). In most patients, irritant and …