[HTML][HTML] Serum complement proteins rather than inflammatory factors is effective in predicting psychosis in individuals at clinical high risk

TH Zhang, JH Zeng, JY Ye, YQ Gao, YG Hu… - Translational …, 2023 - nature.com
Immunological/inflammatory factors are implicated in the development of psychosis.
Complement is a key driver of inflammation; however, it remains unknown which factor is …

Brain morphologic changes in early stages of psychosis: implications for clinical application and early intervention

T Takahashi, M Suzuki - Psychiatry and clinical neurosciences, 2018 - Wiley Online Library
To date, a large number of magnetic resonance imaging (MRI) studies have been conducted
in schizophrenia, which generally demonstrate gray matter reduction, predominantly in the …

Prediction of transition to psychosis in patients with a clinical high risk for psychosis: a systematic review of methodology and reporting

E Studerus, A Ramyead… - Psychological medicine, 2017 - cambridge.org
BackgroundTo enhance indicated prevention in patients with a clinical high risk (CHR) for
psychosis, recent research efforts have been increasingly directed towards estimating the …

[HTML][HTML] Prediction and prevention in the clinical high-risk for psychosis paradigm: a review of the current status and recommendations for future directions of inquiry

MA Worthington, TD Cannon - Frontiers in psychiatry, 2021 - frontiersin.org
Prediction and prevention of negative clinical and functional outcomes represent the two
primary objectives of research conducted within the clinical high-risk for psychosis (CHR-P) …

[HTML][HTML] Outreach and support in South-London (OASIS) 2001—2020: Twenty years of early detection, prognosis and preventive care for young people at risk of …

P Fusar-Poli, T Spencer, A De Micheli, V Curzi… - European …, 2020 - Elsevier
This study aims to describe twenty years of early detection, prognosis and preventive care in
the Outreach and Support In South-London (OASIS) mental health service for individuals at …

Changes in inflammatory balance correlates with conversion to psychosis among individuals at clinical high-risk: a prospective cohort study

TH Zhang, JH Zeng, YY Wei, JY Ye, XC Tang, LH Xu… - Psychiatry …, 2022 - Elsevier
Previous studies have revealed that the imbalance between Th1 cytokines and Th2
cytokines plays a role in disturbance of cellular responses in the brain during psychosis …

[HTML][HTML] Inflammatory biomarkers in schizophrenia: Implications for heterogeneity and neurobiology

BJ Miller, DR Goldsmith - Biomarkers in Neuropsychiatry, 2019 - Elsevier
The longstanding investigation of immune system abnormalities, including inflammation, in
schizophrenia has tremendous renewed interest as an area of research. Presently, the field …

Telepsychotherapy with youth at clinical high risk for psychosis: Clinical issues and best practices during the COVID-19 pandemic.

JS DeLuca, ND Andorko, D Chibani… - Journal of …, 2020 - psycnet.apa.org
La detección temprana y la prevención de psicosis se han hecho una prioridad
internacional. La gran parte de este trabajo se ha enfocado en jóvenes que presentan con …

Reliability, validity, epidemiology, and cultural variation of the Structured Interview for Psychosis-risk Syndromes (SIPS) and the Scale Of Psychosis-risk Symptoms …

SW Woods, BC Walsh, AR Powers… - Handbook of attenuated …, 2019 - Springer
Abstract The Structured Interview for Psychosis-risk Syndromes (SIPS) has been one of most
commonly used instruments worldwide for diagnosing and evaluating subjects with a clinical …

[HTML][HTML] Longitudinal outcome of attenuated positive symptoms, negative symptoms, functioning and remission in people at clinical high risk for psychosis: a meta …

GS de Pablo, F Besana, V Arienti, A Catalan… - …, 2021 - thelancet.com
Background Little is known about clinical outcomes other than transition to psychosis in
people at Clinical High-Risk for psychosis (CHR-P). Our aim was to comprehensively meta …