Neuroinflammation in acute ischemic and hemorrhagic stroke

DL Alsbrook, M Di Napoli, K Bhatia, J Biller… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review This review aims to provide an overview of neuroinflammation
in ischemic and hemorrhagic stroke, including recent findings on the mechanisms and …

The role of gut microbiota in blood–brain barrier disruption after stroke

M Zeng, M Peng, J Liang, H Sun - Molecular Neurobiology, 2023 - Springer
Growing evidence has proved that alterations in the gut microbiota have been linked to
neurological disorders including stroke. Structural and functional disruption of the blood …

The causal effects between gut microbiota and hemorrhagic stroke: a bidirectional two-sample Mendelian randomization study

Y Shen, H Liu, X Meng, A Gao, Y Liu, W Ma… - Frontiers in …, 2023 - frontiersin.org
Background Recent studies have suggested that the composition of gut microbiota (GM)
may change after intracerebral hemorrhage. However, the causal inference of GM and …

Interplay between gut microbiota and NLRP3 inflammasome in intracerebral hemorrhage

Y Zhang, W Yu, C Flynn, W Chang, L Zhang, M Wang… - Nutrients, 2022 - mdpi.com
The pathophysiological process of intracerebral hemorrhage (ICH) is very complex,
involving various mechanisms such as apoptosis, oxidative stress and inflammation. As one …

Mechanisms and clinical implications of human gut microbiota-drug interactions in the precision medicine era

S Wang, D Ju, X Zeng - Biomedicines, 2024 - mdpi.com
The human gut microbiota, comprising trillions of microorganisms residing in the
gastrointestinal tract, has emerged as a pivotal player in modulating various aspects of …

The role of short-chain fatty acids in central nervous system diseases: A bibliometric and visualized analysis with future directions

Z Lan, X Tang, M Lu, Z Hu, Z Tang - Heliyon, 2024 - cell.com
Background Short-chain fatty acids (SCFAs) are thought to play a key role in the microbe-gut-
brain axis and involve in the pathogenesis of a variety of neurological diseases. This study …

Association between oral microbial dysbiosis and poor functional outcomes in stroke-associated pneumonia patients

Y Ren, J Liang, X Li, Y Deng, S Cheng, Q Wu, W Song… - BMC microbiology, 2023 - Springer
Background Despite advances in our understanding of the critical role of the microbiota in
stroke patients, the oral microbiome has rarely been reported to be associated with stroke …

Unravelling the Gut Microbiome Role in Cardiovascular Disease: A Systematic Review and a Meta-Analysis

D Martins, C Silva, AC Ferreira, S Dourado… - Biomolecules, 2024 - mdpi.com
A notable shift in understanding the human microbiome's influence on cardiovascular
disease (CVD) is underway, although the causal association remains elusive. A systematic …

Genetically predicted causality between gut microbiota, blood metabolites, and intracerebral hemorrhage: a bidirectional Mendelian randomization study

T Zhang, G Liu, Y Cao, J Zhao, S Jiang… - Frontiers in …, 2024 - frontiersin.org
Background Recent research linked changes in the gut microbiota and serum metabolite
concentrations to intracerebral hemorrhage (ICH). However, the potential causal …

Intracranial hemorrhage management in the multi-omics era

X Feng, X Li, J Feng, J Xia - Heliyon, 2023 - cell.com
Intracranial hemorrhage (ICH) is a devastating disorder. Neuroprotective strategies that
prevent tissue injury and improve functional outcomes have been identified in multiple …