Accumulating data suggest that type 2 diabetes mellitus (T2DM) in younger people (aged<
40 years), referred to as young-onset T2DM, has a more rapid deterioration of β-cell function …

Insulin resistance changes over time during pregnancy, and in the last half of the pregnancy,
insulin resistance increases considerably and can become severe, especially in women with …

ABSTRACT Gestational Diabetes Mellitus (GDM) is the most common metabolic condition
during pregnancy and may result in short-and long-term complications for both mother and …

Since 1980, global obesity has doubled, and the incidence of cardiometabolic diseases
such as type 2 diabetes and heart disease is also increasing. While genetic susceptibility …

Fetal metabolic programming caused by the adverse intrauterine environment can induce
metabolic syndrome in adult offspring. Adverse intrauterine environment introduces fetal …

Asthma prevalence has been on the increase, especially in North America compared with
other continents. However, the prevalence of asthma differs worldwide, and in many …

Nutrition is a modifiable key factor that is able to interact with both the genome and
epigenome to influence human health and fertility. In particular, specific genetic variants can …

During normal pregnancy, increased insulin resistance acts as an adaptation to enhance
materno-foetal nutrient transfer and meet the nutritional needs of the developing foetus …

Diabetes is a common metabolic complication of pregnancy and affected women fall into two
subgroups: women with pre-existing diabetes and those with gestational diabetes mellitus …

Offspring of women with gestational diabetes mellitus (GDM) are at increased risk of
developing metabolic disease, potentially mediated by epigenetic mechanisms. We …