Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …

Osteoarthritis (OA) is a common degenerative disease characterized by the destruction of
articular cartilage and chronic inflammation of surrounding tissues. Matrix metalloproteinase …

Osteoarthritis (OA) is the most common joint disease worldwide and a leading cause of
disability. Characterized by degradation of articular cartilage, synovial inflammation, and …

Abstract Introduction Resveratrol (3, 5, 4'-trihydroxy-trans-stilbene) is a polyphenol obtained
from diverse groups of plants, especially in the muscadine grape, red wine, lingonberry …

In recent years, accumulating evidence has indicated that long non-coding RNAs (lncRNAs)
are powerful factors influencing the progression of multiple malignancies. Although a …

Osteoarthritis (OA) is currently the most widespread musculoskeletal condition and primarily
affects weight-bearing joints such as the knees and hips. Importantly, knee OA remains a …

Osteoarthitis (OA) is the most common aging-related joint pathology; the aging process
results in changes to joint tissues that ultimately contribute to the development of OA …

Osteoarthritis (OA) is one of the progressing chronic joint associated with by many complex
factors such as age, obesity, and trauma. Knee osteoarthritis (KOA) is the most common type …

Cancer has become a major health issue worldwide, contributing to a high mortality rate.
Tumor metastasis is attributed to the death of most patients. Epithelial-to-mesenchymal …

Background Osteoarthritis (OA) treatment aims to improve inflammation and delay cartilage
degeneration. However, there is no effective strategy presently available. Ononin, a …