The foundations of neurodevelopment across an individual's lifespan are established in the
first 1000 days of life (2 years). During this period an adequate supply of nutrients are …

The blood levels of most vitamins decrease during pregnancy if un-supplemented, including
vitamins A, C, D, K, B1, B3, B5, B6, folate, biotin, and B12. Sub-optimal intake of vitamins …

Importance Nutrition during pregnancy is a critical dimension not only for women's health but
also for the lifelong health of the offspring. Very limited national data exist on the usual …

Why Love Matters explains why loving relationships are essential to brain development in
the early years, and how these early interactions can have lasting consequences for future …

The importance of ensuring adequate choline intakes during pregnancy is increasingly
recognized. Choline is critical for a number of physiological processes during the prenatal …

Background Trace elements and vitamins, named together micronutrients (MNs), are
essential for human metabolism. Recent research has shown the importance of MNs in …

Few studies have examined associations between plasma choline metabolites and risk of
colorectal cancer. Therefore, we investigated associations between plasma biomarkers of …

One carbon metabolism (OCM) is critical for early development, as it provides one carbon
(1C) units for the biosynthesis of DNA, proteins, and lipids and epigenetic modification of the …

Intellectual disability (ID) is the unavoidable hallmark of Down syndrome (DS), with a heavy
impact on public health. Accumulating evidence shows that DS is characterized by …

Numerous rodent studies demonstrate developmental programming of offspring cognition by
maternal choline intake, with prenatal choline deprivation causing lasting adverse effects …