Matching chelators to radiometals for radiopharmaceuticals

EW Price, C Orvig - Chemical Society Reviews, 2014 - pubs.rsc.org
Radiometals comprise many useful radioactive isotopes of various metallic elements. When
properly harnessed, these have valuable emission properties that can be used for …

Comparison of Gallium-68 and Fluorine-18 imaging characteristics in positron emission tomography

A Sanchez-Crespo - Applied Radiation and Isotopes, 2013 - Elsevier
This review article compares PET imaging performance with Gallium-68 (68Ga) and
Fluorine-18 (18F). The literature on this topic is scarce; hence in order to complete the …

Convection-enhanced delivery for diffuse intrinsic pontine glioma: a single-centre, dose-escalation, phase 1 trial

MM Souweidane, K Kramer, N Pandit-Taskar… - The Lancet …, 2018 - thelancet.com
Background Diffuse intrinsic pontine glioma is one of the deadliest central nervous system
tumours of childhood, with a median overall survival of less than 12 months. Convection …

Nuclear data for production and medical application of radionuclides: present status and future needs

SM Qaim - Nuclear medicine and biology, 2017 - Elsevier
Introduction The significance of nuclear data in the choice and medical application of a
radionuclide is considered: the decay data determine its suitability for organ imaging or …

PET tracers based on Zirconium-89

Y Zhang, H Hong, W Cai - Current radiopharmaceuticals, 2011 - ingentaconnect.com
Positron emission tomography (PET) imaging with radiolabeled monoclonal antibodies has
always been a dynamic area in molecular imaging. With decay half-life (3.3 d) well matched …

Radiohalogens for imaging and therapy

MJ Adam, DS Wilbur - Chemical Society Reviews, 2005 - pubs.rsc.org
Radiohalogens play a very important role in radiopharmaceuticals used for medical imaging
(now referred to as molecular imaging) and therapy applications. Development of new …

Molecular imaging with copper-64

SV Smith - Journal of inorganic biochemistry, 2004 - Elsevier
Molecular imaging is expected to change the face of drug discovery and development. The
ability to link imaging to biology for guiding therapy should improve the rate at which novel …

Unconventional nuclides for radiopharmaceuticals

JP Holland, MJ Williamson, JS Lewis - Molecular imaging, 2010 - journals.sagepub.com
Rapid and widespread growth in the use of nuclear medicine for both diagnosis and therapy
of disease has been the driving force behind burgeoning research interests in the design of …

Radioimmunoimaging with longer-lived positron-emitting radionuclides: potentials and challenges

TK Nayak, MW Brechbiel - Bioconjugate chemistry, 2009 - ACS Publications
Radioimmunoimaging and therapy has been an area of interest for several decades. Steady
progress has been made toward clinical translation of radiolabeled monoclonal antibodies …

[HTML][HTML] Diffuse intrinsic pontine glioma: molecular landscape, evolving treatment strategies and emerging clinical trials

S Damodharan, M Lara-Velazquez… - Journal of Personalized …, 2022 - mdpi.com
Diffuse intrinsic pontine glioma (DIPG) is a type of intrinsic brainstem glial tumor that occurs
primarily in the pediatric population. DIPG is initially diagnosed based on clinical symptoms …