Onset dynamics of type A botulinum neurotoxin-induced paralysis

FJ Lebeda, M Adler, K Erickson, Y Chushak - Journal of pharmacokinetics …, 2008 - Springer
Experimental studies have demonstrated that botulinum neurotoxin serotype A (BoNT/A)
causes flaccid paralysis by a multi-step mechanism. Following its binding to specific …

Defense against biological weapons (Biodefense)

VS Georgiev - National Institute of Allergy and Infectious Diseases …, 2009 - Springer
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Comparison of the structural features of botulinum neurotoxin and NTNH, a non-toxic accessory protein of the progenitor complex

KM Krebs, FJ Lebeda - The Botulinum Journal, 2008 - inderscienceonline.com
The non-toxic, non-hemagglutinin (NTNH) protein occurs with the seven progenitor
serotypes of the botulinum neurotoxins (BoNTs). Bioinformatic techniques predict that the N …

Accelerating botulism therapeutic product development in the Department of Defense

AM Stahl, M Adler, CB Millard… - Drug Development …, 2009 - Wiley Online Library
Coordinated small‐molecule drug discovery research efforts for the treatment of botulism by
the public sector, especially the US Department of Defense (DoD) and Department of Health …

New routes in the high-throughput screening of toxic proteins using immunochemical tools

M Puiu, C Bala - Biosensors for Security and Bioterrorism Applications, 2016 - Springer
The chapter reviews several aspects related to the mechanism of action of toxic proteins
used as biological warfare agents, together with the latest advances in immunosensor …

[PDF][PDF] Incidencia del Síndrome de Frey diagnosticado mediante Test de Minor y su tratamiento con Toxina Botulínica

MJL Navarro, M José - 2015 - roderic.uv.es
Al Dr. D. Constantino Morera Pérez, Director de esta Tesis Doctoral, por su apoyo y
motivación, por transmitir su dedicación e inculcar sus valores. Al Dr. D. José Mª Perolada …

[PDF][PDF] Dual-Use Dilemmas in Biotechnology: Examples, Issues and Concerns

AT Khalil, SA Jan - Dual-Use Education Concerns in Biotechnology … - academia.edu
Benign research in life sciences has massive potential to be misused, either intentionally or
unintentionally. The rapid growth in biotechnology in recent years has offered great benefits …