Biological entities are involved in intricate and complex interactions, in which uncovering the
biological information from the network concepts are of great significance. Benefiting from …

The graph orientation problem calls for orienting the edges of a graph so as to maximize the
number of pre-specified source–target vertex pairs that admit a directed path from the source …

State-of-the-art omics technologies provide molecular insights into various biological
contexts, such as disease states, patients, and drug perturbations. Network inference and …

Motivation A chief goal of systems biology is the reconstruction of large-scale executable
models of cellular processes of interest. While accurate continuous models are still beyond …

El funcionament intern de les cèl· lules pot entendre's com un conjunt d'interaccions entre
biomolècules, formant una xarxa que coneixem amb el nom d'interactoma. Els fàrmacs i …

Cancer constantly evolves to evade the host immune system and resist different treatments.
As a consequence, we see a wide range of inter and intra-tumor heterogeneity. In this PhD …

Chemical compounds are the daily working environment of a chemist. Therefore, a typical
workflow of an experimentally working chemist might be to perform a synthesis under certain …

Biologists often screen an entire genome for involvement in a cellular phenotype of interest.
To analyze the resulting data, computational methods have been developed to infer …

Despite the large quantity of information available, thorough researches in various biological
databases are still needed in order to reconstruct and understand the steps that lead to …