Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

Osteoarthritis (OA) is a complicated degenerative disease that affects whole joint tissue.
Currently, apart from surgical approaches to treat late stage OA, effective treatments to …

Background Osteoarthritis (OA) is the most common joint disease and is the leading cause
of chronic disability among older people. Chondrocyte death and extracellular matrix (ECM) …

Osteoarthritis (OA) is a degenerative joint disease involving cartilage. Exosomes derived
from Mesenchymal stem cells (MSCs) therapy improves articular cartilage repair, but …

Autophagy is a highly conserved process that maintains cellular homeostasis during
evolution. Autophagy can occur in the form of macroautophagy, microautophagy or …

Polycystic ovary syndrome (PCOS) is a disease in which endocrine metabolic abnormalities
coexist with reproductive system abnormalities, with the main clinical manifestations …

Osteoarthritis (OA) is the most common degenerative joint disease in the world. Gene
therapy based on delivering microRNAs (miRNAs) into cells has potential for the treatment …

Temporomandibular joint (TMJ) osteoarthritis is a common chronic degenerative disease of
the TMJ. In order to explore its aetiology and pathological mechanism, many animal models …

In cartilage, chondrocytes are responsible for the biogenesis and maintenance of the
extracellular matrix (ECM) composed of proteins, glycoproteins and proteoglycans. Various …

Osteoarthritis (OA) is a degenerative joint disorder causing pain and functional disability.
Emerging evidence reveals that circular RNAs (circRNAs) play essential roles in OA …