Neural functions of hypothalamic oxytocin and its regulation

P Wang, SC Wang, X Liu, S Jia, X Wang, T Li… - ASN …, 2022 - journals.sagepub.com
Oxytocin (OT), a nonapeptide, has a variety of functions. Despite extensive studies on OT
over past decades, our understanding of its neural functions and their regulation remains …

Classic psychedelics and alcohol use disorders: A systematic review of human and animal studies

J Calleja‐Conde, JA Morales‐García… - Addiction …, 2022 - Wiley Online Library
Classic psychedelics refer to substances such as lysergic acid diethylamide (LSD),
psilocybin, ayahuasca, and mescaline, which induce altered states of consciousness by …

[HTML][HTML] Brain region-and sex-specific transcriptional profiles of microglia

K Barko, M Shelton, X Xue, Y Afriyie-Agyemang… - Frontiers in …, 2022 - frontiersin.org
Microglia are resident macrophages of the brain, performing roles related to brain
homeostasis, including modulation of synapses, trophic support, phagocytosis of apoptotic …

Treatment-resistant depression with anhedonia: integrating clinical and preclinical approaches to investigate distinct phenotypes

CA Kelly, KB Freeman, JA Schumacher - Neuroscience & Biobehavioral …, 2022 - Elsevier
In our clinical work with treatment-resistant depressed (TRD) patients, certain patterns have
emerged in terms of patients' presentations of anhedonia. Multiple studies have investigated …

Sexual health and serotonin 4 receptor brain binding in unmedicated patients with depression—a NeuroPharm study

AL Rasmussen, SV Larsen, B Ozenne… - Translational …, 2023 - nature.com
Sexual dysfunction is prominent in Major Depressive Disorder (MDD) and affects women
with depression more than men. Patients with MDD relative to healthy controls have lower …

[HTML][HTML] Raphe serotonin projections dynamically regulate feeding behavior through targeting inhibitory circuits from rostral zona incerta to paraventricular thalamus

Q Ye, J Nunez, X Zhang - Molecular Metabolism, 2022 - Elsevier
Objective Rostral zona incerta (ZIR) evokes feeding by sending GABA transmission to
paraventricular thalamus (PVT). Although central serotonin (5-HT) signaling is known to play …

Molecular Design of SERTlight: A Fluorescent Serotonin Probe for Neuronal Labeling in the Brain

WL Lee, X Westergaard, C Hwu, J Hwu… - Journal of the …, 2024 - ACS Publications
The serotonergic transmitter system plays fundamental roles in the nervous system in
neurotransmission, synaptic plasticity, pathological processes, and therapeutic effects of …

Deleting Snord115 genes in mice remodels monoaminergic systems activity in the brain toward cortico-subcortical imbalances

V Marty, JJ Butler, B Coutens, O Chargui… - Human Molecular …, 2023 - academic.oup.com
The neuronal-specific SNORD115 has gathered interest because its deficiency may
contribute to the pathophysiology of Prader-Willi syndrome (PWS), possibly by altering post …

Environmentally-relevant concentrations of the antipsychotic drugs sulpiride and clozapine induce abnormal dopamine and serotonin signaling in zebrafish brain

B Zhang, X Peng, X Sun, Y Guo, T Li - Scientific Reports, 2022 - nature.com
The presence of drugs in surface and groundwaters adversely affects the physiological
function of non-target organisms due special activities that can pose a serious threats to …

The Serotonergic System and Amyotrophic Lateral Sclerosis: A Review of Current Evidence

L Yang, Y Cheng, Y Zhu, L Cui, X Li - Cellular and Molecular …, 2023 - Springer
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by the
premature death of motor neurons. Serotonin (5-HT) is a crucial neurotransmitter, and its …